Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Zanamivir
Drug ID BADD_D02380
Description A guanido-neuraminic acid that is used to inhibit neuraminidase.
Indications and Usage For the prevention and treatment of influenza A and B.
Marketing Status Prescription
ATC Code J05AH01
DrugBank ID DB00558
KEGG ID D00902
MeSH ID D053243
PubChem ID 60855
TTD Drug ID D00NPP
NDC Product Code 0173-0681; 63379-028
Synonyms Zanamivir | 2,3-Didehydro-2,4-Dideoxy-4-Guanidinyl-N-Acetylneuraminic Acid | 4-Guanidino-2,4-Dideoxy-2,3-Didehydro-N-Acetylneuraminic Acid | 5-Acetylamino-2,6-Anhydro-4-Guanidino-3,4,5-Trideoxy-D-Galacto-Non-Enoic Acid | 4-Guanidino-Neu5Ac2en | 4 Guanidino Neu5Ac2en | 2,3-Didehydro-2,4-Dideoxy-4-Guanidino-N-Acetyl-D-Neuraminic Acid | 4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic Acid | 4 Guanidino 2 Deoxy 2,3 Didehydro N Acetylneuraminic Acid | Acid, 4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic | Relenza | GG 167 | GG167 | GG-167
Chemical Information
Molecular Formula C12H20N4O7
CAS Registry Number 139110-80-8
SMILES CC(=O)NC1C(C=C(OC1C(C(CO)O)O)C(=O)O)N=C(N)N
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation17.02.05.012; 19.06.02.001--
Altered state of consciousness17.02.04.001; 19.07.01.003--Not Available
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Asthma10.01.03.010; 22.03.01.002--Not Available
Body temperature increased13.15.01.001--Not Available
Bronchitis11.01.09.001; 22.07.01.001--
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.001--
Chills08.01.09.001; 15.05.03.016--
Confusional state17.02.03.005; 19.13.01.001--
Cough22.02.03.001--
Dehydration14.05.05.001--
Delirium19.13.02.001--
Delusion19.10.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Dyspnoea02.01.03.002; 22.02.01.004--
Ear haemorrhage04.03.01.002; 24.07.01.004--Not Available
Ear infection04.03.01.006; 11.01.05.001--Not Available
Ear pain04.03.01.003--
Epistaxis22.04.03.001; 24.07.01.005--
Erythema multiforme10.01.03.015; 23.03.01.003--
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