Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Zanamivir
Drug ID BADD_D02380
Description A guanido-neuraminic acid that is used to inhibit neuraminidase.
Indications and Usage For the prevention and treatment of influenza A and B.
Marketing Status approved; investigational
ATC Code J05AH01
DrugBank ID DB00558
KEGG ID D00902
MeSH ID D053243
PubChem ID 60855
TTD Drug ID D00NPP
NDC Product Code 0173-0681; 63379-028
UNII L6O3XI777I
Synonyms Zanamivir | 2,3-Didehydro-2,4-Dideoxy-4-Guanidinyl-N-Acetylneuraminic Acid | 4-Guanidino-2,4-Dideoxy-2,3-Didehydro-N-Acetylneuraminic Acid | 5-Acetylamino-2,6-Anhydro-4-Guanidino-3,4,5-Trideoxy-D-Galacto-Non-Enoic Acid | 4-Guanidino-Neu5Ac2en | 4 Guanidino Neu5Ac2en | 2,3-Didehydro-2,4-Dideoxy-4-Guanidino-N-Acetyl-D-Neuraminic Acid | 4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic Acid | 4 Guanidino 2 Deoxy 2,3 Didehydro N Acetylneuraminic Acid | Acid, 4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic | Relenza | GG 167 | GG167 | GG-167
Chemical Information
Molecular Formula C12H20N4O7
CAS Registry Number 139110-80-8
SMILES CC(=O)NC1C(C=C(OC1C(C(CO)O)O)C(=O)O)N=C(N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.000282%
Acute respiratory distress syndrome10.02.01.067; 22.01.03.001; 24.03.02.0340.000847%
Acute respiratory failure14.01.04.004; 22.02.06.0010.000282%-
Ageusia07.14.03.003; 17.02.07.0010.000282%-
Aggression19.05.01.0010.000706%-
Agitation17.02.05.012; 19.06.02.0010.001044%
Altered state of consciousness17.02.04.001; 19.07.01.0030.000988%-
Anaphylactic reaction10.01.07.001; 24.06.03.0060.000423%
Anaphylactic shock10.01.07.002; 24.06.02.0040.000282%-
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Anxiety19.06.02.002--
Arrhythmia02.03.02.001---
Arthralgia15.01.02.001--
Asthenia08.01.01.001---
Asthma10.01.03.010; 22.03.01.0020.000282%-
Blister12.01.06.002; 23.03.01.0010.000423%-
Body temperature increased13.15.01.001---
Bronchitis11.01.09.001; 22.07.01.001--
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.0010.000565%
Chills08.01.09.001; 15.05.03.016--
Confusional state17.02.03.005; 19.13.01.001--
Cough22.02.03.0010.000423%
Death08.04.01.0010.003528%
Dehydration14.05.05.0010.000282%
Delirium19.13.02.0010.001327%
Delusion19.10.01.001--
Depressed level of consciousness17.02.04.0020.000988%
Dermatitis23.03.04.002---
Diarrhoea07.02.01.0010.001552%
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