Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Tetraferric tricitrate decahydrate
Drug ID BADD_D02184
Description Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease.[A25965] Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.[L9926]
Indications and Usage Tetraferric tricitrate decahydrate is indicated to control serum phosphorous in adults with chronic kidney disease who require dialysis.[L9926] Tetraferric tricitrate decahydrate is also indicated to treat iron deficiency anemia in adults with chronic kidney disease who are not on dialysis.[L9926]
Marketing Status approved
ATC Code V03AE08
DrugBank ID DB14520
KEGG ID Not Available
MeSH ID Not Available
PubChem ID 90478690
TTD Drug ID Not Available
NDC Product Code 63474-300
UNII Q91187K011
Synonyms Not Available
Chemical Information
Molecular Formula C18H32Fe4O31
CAS Registry Number Not Available
SMILES C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])[O-].C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])[O- ].C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])[O-].O.O.O.O.O.O.O.O.O.O.[Fe+3].[Fe+3].[Fe +3].[Fe+3]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Increased appetite08.01.09.027; 14.03.01.0030.004213%-
Myocardial infarction02.02.02.007; 24.04.04.0090.005576%
Nausea07.01.07.001--
Neoplasm malignant16.16.01.0010.001239%-
Palpitations02.11.04.0120.006319%
Pregnancy18.08.02.0040.004833%-
Pruritus23.03.12.0010.045476%
Pulmonary oedema02.05.02.003; 22.01.03.0030.001239%
Rash23.03.13.0010.046963%-
Rash pruritic23.03.13.0300.004213%-
Rectal haemorrhage07.12.03.001; 24.07.02.0180.006319%
Skin discolouration23.03.03.0050.008426%-
Skin exfoliation23.03.07.0030.006939%-
Skin irritation23.03.04.0090.004213%-
Swelling face08.01.03.100; 10.01.05.018; 23.04.01.0180.008426%-
Tongue discolouration07.14.02.0060.004213%-
Tooth discolouration07.09.02.0010.004213%
Vaginal haemorrhage21.08.01.001; 24.07.03.0050.004213%
Vomiting07.01.07.003--
Abdominal symptom07.01.06.0070.008426%-
Cardiac disorder02.11.01.0030.003717%-
Cardiac valve disease02.07.02.0010.001239%-
Drug intolerance08.06.01.0130.028004%-
Pigmentation disorder23.05.03.0010.004213%-
Iron overload12.02.08.005; 14.13.03.0020.001239%
Gastrointestinal tract mucosal pigmentation07.11.03.0090.004213%-
Treatment noncompliance08.06.01.067; 12.09.02.0060.005452%-
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