Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Testosterone
Drug ID BADD_D02170
Description Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.[A186943]
Indications and Usage Testosterone is indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995]
Marketing Status approved; investigational
ATC Code G03BA03
DrugBank ID DB00624
KEGG ID D00075
MeSH ID D013739
PubChem ID 6013
TTD Drug ID D06XMU
NDC Product Code 0832-1120; 65089-0050; 43598-304; 49884-418; 63629-8455; 63629-9310; 0591-2925; 38779-2936; 43647-568; 43742-1436; 73774-014; 76003-1083; 43742-1242; 0245-0871; 62332-552; 70700-112; 76420-685; 76420-687; 76420-699; 24979-130; 45802-610; 0051-8462; 64380-151; 68180-943; 69097-363; 0591-2363; 0603-7831; 0009-5020; 44132-006; 49452-7658; 64025-0010; 45802-281; 0245-0872; 0023-5992; 63629-2125; 64380-152; 66887-001; 0591-2114; 0591-2924; 0591-2926; 0591-3216; 0832-1121; 51927-0267; 70492-002; 76420-684; 0009-0074; 12875-8248; 22552-0009; 49452-7652; 60592-721; 60870-0251; 16714-967; 17139-562; 63629-2124; 68180-941; 44132-008; 48087-0113; 51552-0029; 42667-5511; 63481-183; 63629-2352; 69238-1013; 0591-3217; 0591-3524; 38779-0163; 38779-2598; 82393-113; 24979-078; 45802-366; 66887-004; 51552-0564; 62991-2150; 76420-686; 16714-969; 45802-754; 49884-510; 62332-488; 69339-158; 0591-2921; 49452-7657; 16714-968; 0023-5990
UNII 3XMK78S47O
Synonyms Testosterone | 17-beta-Hydroxy-4-Androsten-3-one | 17 beta Hydroxy 4 Androsten 3 one | Androtop | Histerone | Sterotate | Sustanon | Androderm | Testoderm | Testolin | Testopel | Testosterone Sulfate | AndroGel | 8-Isotestosterone | 8 Isotestosterone | 17-beta-Hydroxy-8 alpha-4-Androsten-3-one | 17 beta Hydroxy 8 alpha 4 Androsten 3 one | Andropatch | Testim
Chemical Information
Molecular Formula C19H28O2
CAS Registry Number 58-22-0
SMILES CC12CCC3C(C1CCC2O)CCC4=CC(=O)CCC34C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood bilirubin increased13.03.04.018--
Blood cholesterol increased13.12.01.002--
Blood creatinine increased13.13.01.004--
Blood glucose increased13.02.02.002---
Blood pressure diastolic decreased13.14.03.003---
Blood pressure increased13.14.03.005---
Blood pressure systolic increased13.14.03.006---
Blood prolactin increased13.10.03.002---
Blood testosterone decreased13.10.05.004---
Blood testosterone increased13.10.05.002---
Blood triglycerides increased13.12.03.001---
Blood urea normal13.13.01.023---
Brain stem infarction17.08.01.024; 24.04.06.0140.000227%-
Breast cyst16.14.01.004; 21.05.01.006---
Breast enlargement21.05.04.001---
Breast induration21.05.05.010---
Breast mass21.05.04.0020.000354%-
Breast pain21.05.05.003--
Breast tenderness21.05.05.0040.000772%-
Bronchitis11.01.09.001; 22.07.01.001--
Bundle branch block right02.03.01.0110.000136%-
Cardiac arrest02.03.04.0010.003681%
Cardiac failure02.05.01.0010.001500%
Cardiac failure congestive02.05.01.0020.003317%-
Cardio-respiratory arrest02.03.04.002; 22.02.06.0070.001227%-
Cardiogenic shock02.05.01.003; 24.06.02.0060.000500%-
Cardiomegaly02.04.02.0010.000273%-
Cardiomyopathy02.04.01.0010.000636%-
Cardiovascular disorder02.11.01.010; 24.03.02.0090.007261%-
Carotid artery stenosis17.08.02.001; 24.04.06.0010.000318%-
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