Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Secobarbital sodium
Drug ID BADD_D01998
Description Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Indications and Usage For the Short-term treatment of intractable insomnia for patients habituated to barbiturates
Marketing Status approved; vet_approved
ATC Code N05CA06
DrugBank ID DB00418
KEGG ID D01310
MeSH ID D012631
PubChem ID 14148199
TTD Drug ID D00SJE
NDC Product Code 0792-0128
UNII XBP604F6UM
Synonyms Secobarbital | Meballymal | Quinalbarbitone | Sebar | Seconal Sodium | Seconal | Secobarbital Sodium | Sodium, Secobarbital
Chemical Information
Molecular Formula C12H17N2NaO3
CAS Registry Number 309-43-3
SMILES CCCC(C)C1(C(=O)NC(=O)[N-]C1=O)CC=C.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation17.02.05.012; 19.06.02.001--
Anaemia megaloblastic01.03.02.003; 14.12.01.003---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Ataxia08.01.02.004; 17.02.02.001--
Bradycardia02.03.02.002---
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Depressed level of consciousness17.02.04.002--
Dermatitis exfoliative10.01.01.004; 23.03.07.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Hallucination19.10.04.003--
Headache17.14.01.001--
Hyperkinesia17.01.02.008---
Hypotension24.06.03.002--
Hypoventilation22.02.01.007---
Injection site reaction08.02.03.014; 12.07.03.015--
Insomnia17.15.03.002; 19.02.01.002--
Nausea07.01.07.001--
Nervousness19.06.02.003---
Nightmare19.02.03.003---
Pyrexia08.05.02.003--
Rash23.03.13.001---
Somnolence17.02.04.006; 19.02.05.003--
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Thinking abnormal17.02.05.023; 19.10.03.001---
Vomiting07.01.07.003--
Mental disorder19.07.01.002---
Liver injury09.01.07.022; 12.01.17.012---
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