Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Secobarbital
Drug ID BADD_D01997
Description Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Indications and Usage For the Short-term treatment of intractable insomnia for patients habituated to barbiturates
Marketing Status approved; vet_approved
ATC Code N05CA06
DrugBank ID DB00418
KEGG ID D00430
MeSH ID D012631
PubChem ID 5193
TTD Drug ID D00SJE
NDC Product Code Not Available
UNII 1P7H87IN75
Synonyms Secobarbital | Meballymal | Quinalbarbitone | Sebar | Seconal Sodium | Seconal | Secobarbital Sodium | Sodium, Secobarbital
Chemical Information
Molecular Formula C12H18N2O3
CAS Registry Number 76-73-3
SMILES CCCC(C)C1(C(=O)NC(=O)NC1=O)CC=C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lethargy08.01.01.008; 17.02.04.003; 19.04.04.004--
Loss of consciousness17.02.04.004---
Mental disability26.01.01.001---
Nausea07.01.07.001--
Nervousness19.06.02.003---
Nightmare19.02.03.003---
Oedema08.01.07.006; 14.05.06.010---
Pruritus23.03.12.001--
Rash23.03.13.001---
Rash macular23.03.13.003---
Rash maculo-papular23.03.13.004--
Rash papular23.03.13.017---
Respiratory failure14.01.04.003; 22.02.06.002--
Restlessness17.02.05.021; 19.11.02.002--
Shock24.06.02.002---
Somnolence17.02.04.006; 19.02.05.003--
Suicide attempt19.12.01.004--
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Tension19.06.02.005---
Thinking abnormal17.02.05.023; 19.10.03.001---
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
Liver injury09.01.07.022; 12.01.17.012---
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