Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Rivastigmine tartrate
Drug ID BADD_D01956
Description Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Indications and Usage For the treatment of mild to moderate dementia associated with Parkinson's disease or of the Alzheimer's type.
Marketing Status approved; investigational
ATC Code N06DA03
DrugBank ID DB00989
KEGG ID D02558
MeSH ID D000068836
PubChem ID 6918078
TTD Drug ID D0WY5Q
NDC Product Code 0904-7107; 53104-7571; 33342-091; 62332-064; 62332-066; 71209-013; 71209-014; 71209-015; 72241-012; 33342-090; 51991-795; 55111-352; 62756-148; 65862-650; 46708-063; 46708-064; 55111-354; 62135-902; 62756-145; 62756-147; 60687-574; 62135-901; 62756-146; 72241-014; 75834-133; 65862-612; 65862-648; 33342-092; 62135-903; 72241-011; 75834-136; 49706-1826; 65862-651; 46708-066; 55111-066; 55111-353; 55111-355; 62332-063; 65862-649; 71209-012; 72241-013; 75834-135; 62704-0122; 65372-1152; 33342-089; 51991-793; 50379-0012; 46708-065; 51991-794; 62135-900; 62332-065; 75834-134; 51991-796
UNII 9IY2357JPE
Synonyms Rivastigmine | (S)-N-Ethyl-3-((1-dimethyl-amino)ethyl)-N-methylphenylcarbamate | RivastigmineTartrate | Rivastigmine Hydrogen Tartrate | Hydrogen Tartrate, Rivastigmine | Tartrate, Rivastigmine Hydrogen | Exelon | ENA 713 | 713, ENA | SDZ ENA 713 | 713, SDZ ENA | ENA 713, SDZ | ENA-713 | ENA713
Chemical Information
Molecular Formula C18H28N2O8
CAS Registry Number 129101-54-8
SMILES CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Arthropathy15.01.01.003---
Asthenia08.01.01.001---
Ataxia08.01.02.004; 17.02.02.001--
Atrial fibrillation02.03.03.002--
Atrioventricular block02.03.01.002---
Atrophic vulvovaginitis21.02.01.003---
Back pain15.03.04.005--
Basal cell carcinoma16.03.02.001; 23.08.02.001---
Benign prostatic hyperplasia21.04.02.001---
Bladder cancer16.08.01.001; 20.03.04.001---
Bladder pain20.02.02.001---
Blepharitis06.04.04.001; 23.03.04.012---
Blepharospasm06.05.01.001; 17.17.02.001---
Blister12.01.06.002; 23.03.01.001---
Blood creatine phosphokinase increased13.04.01.001--
Blood prolactin increased13.10.03.002---
Body temperature decreased13.15.01.010---
Body temperature increased13.15.01.001---
Bone disorder15.02.04.004---
Bone pain15.02.01.001--
Bradycardia02.03.02.002---
Bradykinesia17.01.02.004---
Breast cancer16.10.01.001; 21.05.01.003---
Breast pain21.05.05.003--
Breath odour07.01.06.002---
Bronchitis11.01.09.001; 22.07.01.001--
Bronchospasm10.01.03.012; 22.03.01.004--
Bundle branch block02.03.01.009---
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