Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prednisolone
Drug ID BADD_D01831
Description Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Indications and Usage Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.[L9542]
Marketing Status approved; vet_approved
ATC Code A01AC04; A07EA01; C05AA04; D07AA03; D07XA02; H02AB06; R01AD02; S01BA04; S01CB02; S02BA03; S03BA02
DrugBank ID DB00860
KEGG ID D00472
MeSH ID D011239
PubChem ID 5755
TTD Drug ID D0D1SG
NDC Product Code 38779-0150; 64958-0097; 82298-104; 67296-1656; 50383-042; 59651-491; 63187-466; 0527-5406; 65089-0038; 50090-0655; 57582-004; 62135-437; 73534-505; 49452-5980; 82298-105; 82298-106; 60592-911; 60722-3001; 51927-0234; 22552-0052
UNII 9PHQ9Y1OLM
Synonyms Prednisolone | Predate | Predonine | Di-Adreson-F | Di Adreson F | DiAdresonF
Chemical Information
Molecular Formula C21H28O5
CAS Registry Number 50-24-8
SMILES CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Atelectasis22.01.02.0010.000157%
Atrial fibrillation02.03.03.0020.000629%
Atrioventricular block02.03.01.0020.000052%-
Atrioventricular block complete02.03.01.0030.000175%
Atrophy08.03.04.001---
Autoimmune hepatitis09.01.07.019; 10.04.09.0010.000070%-
Autonomic nervous system imbalance08.01.01.010; 17.05.01.011; 24.06.01.0050.000035%-
Azotaemia20.01.01.0010.000070%-
B-cell lymphoma01.15.01.001; 16.28.01.0010.000175%-
Bile duct cancer09.04.02.001; 16.07.01.0010.000052%-
Bladder dilatation20.03.01.0070.000035%-
Blindness06.02.10.003; 17.17.01.0030.000227%-
Blindness transient06.02.10.006; 17.17.01.0040.000052%-
Blindness unilateral06.02.10.007; 17.17.01.0160.000035%-
Blister12.01.06.002; 23.03.01.001---
Bone disorder15.02.04.0040.000350%-
Bowen's disease16.03.02.004; 23.08.02.0040.000035%-
Bradycardia02.03.02.002---
Brain compression17.07.02.0050.000035%-
Brain stem infarction17.08.01.024; 24.04.06.0140.000035%-
Breast enlargement21.05.04.0010.000070%-
Breech presentation18.03.04.0010.000035%-
Bronchiectasis22.03.02.0050.000052%-
Bronchospasm10.01.03.012; 22.03.01.0040.000175%
Bundle branch block left02.03.01.0070.000035%-
Bundle branch block right02.03.01.0110.000087%-
Cachexia08.01.01.009; 14.03.02.001; 16.32.03.0110.000035%-
Carbohydrate tolerance decreased13.02.02.003---
Cardiac arrest02.03.04.001--
Cardiac failure02.05.01.0010.000594%
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ADReCS-Target
Drug Name ADR Term Target
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