Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nitrazepam
Drug ID BADD_D01573
Description A benzodiazepine derivative used as an anticonvulsant and hypnotic.
Indications and Usage Used to treat short-term sleeping problems (insomnia), such as difficulty falling asleep, frequent awakenings during the night, and early-morning awakening.
Marketing Status approved
ATC Code N05CD02
DrugBank ID DB01595
KEGG ID D00531
MeSH ID D009567
PubChem ID 4506
TTD Drug ID D0T5WK
NDC Product Code Not Available
UNII 9CLV70W7HS
Synonyms Nitrazepam | Nitrodiazepam | Dormo-Puren | Eatan | Imadorm | Imeson | Mogadon | Nitrazadon | Nitrazep | Nitrazepam AL | Nitrazepam-Neuraxpharm | Nitrazepam Neuraxpharm | Novanox | Radedorm | Remnos | Serenade | Somnite | Rhoxal-Nitrazepam | Rhoxal Nitrazepam | Alodorm | Dormalon
Chemical Information
Molecular Formula C15H11N3O3
CAS Registry Number 146-22-5
SMILES C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Abnormal dreams17.15.02.001; 19.02.03.001---
Aggression19.05.01.001---
Agitation17.02.05.012; 19.06.02.001--
Agranulocytosis01.02.03.001---
Amnesia17.03.02.001; 19.20.01.001--
Anger19.04.02.001---
Anxiety19.06.02.002--
Asthenia08.01.01.001---
Ataxia08.01.02.004; 17.02.02.001--
Body temperature decreased13.15.01.010---
Confusional state17.02.03.005; 19.13.01.001--
Congenital anomaly03.02.01.001---
Constipation07.02.02.001--
Coordination abnormal17.02.02.004---
Delirium tremens08.06.02.006; 12.03.01.037; 19.13.02.002---
Depressed level of consciousness17.02.04.002--
Depression suicidal19.15.01.004---
Dermatitis23.03.04.002---
Developmental delay08.01.03.037; 19.07.05.003---
Diarrhoea07.02.01.001--
Diplopia06.02.06.002; 17.17.01.005---
Disorientation17.02.05.015; 19.13.01.002---
Dissociation19.14.01.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Drug withdrawal syndrome08.06.02.004; 19.07.06.013---
Dysarthria17.02.08.001; 19.19.03.001--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dysphoria19.04.02.004---
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