Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Methazolamide
Drug ID BADD_D01410
Description A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Indications and Usage For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma
Marketing Status Prescription; Discontinued
ATC Code S01EC05
DrugBank ID DB00703
KEGG ID D00655
MeSH ID D008704
PubChem ID 4100
TTD Drug ID D0C2II
NDC Product Code 42571-239; 0574-0790; 42571-240; 62559-240; 51407-026; 55806-021; 72969-047; 63629-1986; 50090-3233; 11712-530; 69575-4008; 63629-1958; 0574-0791; 62559-241; 48954-472; 68682-022; 11712-007; 71052-045; 68682-023; 51407-027; 63629-1987; 55806-020
Synonyms Methazolamide | N-Methylacetazolamide | N Methylacetazolamide
Chemical Information
Molecular Formula C5H8N4O3S2
CAS Registry Number 554-57-4
SMILES CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001--Not Available
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Aplastic anaemia01.03.03.002--Not Available
Asthenia08.01.01.001--Not Available
Body temperature increased13.15.01.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Crystalluria20.02.01.003--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspepsia07.01.02.001--
Electrolyte imbalance14.05.01.002--Not Available
Erythema multiforme10.01.03.015; 23.03.01.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Glycosuria20.02.01.005--
Haematuria20.02.01.006; 24.07.01.047--
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatic necrosis09.01.07.002--
Leukopenia01.02.02.001--Not Available
Malaise08.01.01.003--
Melaena07.12.02.004; 24.07.02.013--Not Available
Metabolic acidosis14.01.01.003--Not Available
Myopia06.02.04.002--Not Available
Nausea07.01.07.001--
Nephrolithiasis20.04.01.002--
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