Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lithium carbonate
Drug ID BADD_D01303
Description Lithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Indications and Usage Lithium is used as a mood stabilizer, and is indicated for the treatment of manic episodes and maintenance of bipolar disorder[FDA Label].
Marketing Status approved
ATC Code Not Available
DrugBank ID DB14509
KEGG ID D00801
MeSH ID D016651
PubChem ID 11125
TTD Drug ID D04UUH
NDC Product Code 31722-546; 62332-148; 62756-430; 63187-304; 64980-205; 68462-221; 70518-0608; 70518-2312; 70518-2345; 70518-3565; 72789-171; 72789-172; 31722-544; 62332-014; 68071-2714; 0054-8531; 46708-303; 55154-4920; 63629-1916; 0378-1450; 70518-0668; 70518-3681; 0054-4527; 62332-013; 68462-220; 68462-222; 68462-223; 70518-0437; 70518-2699; 68084-655; 70518-1434; 0054-2531; 71335-0120; 0054-8528; 0615-8302; 50090-3917; 58118-0545; 0054-8526; 51079-142; 63629-1917; 68462-224; 71610-557; 72789-173; 39345-5104; 46708-305; 0378-1300; 64980-278; 70518-1753; 70518-2086; 0054-2526; 31722-545; 50090-1470; 62332-015; 62559-280; 0054-0020; 68428-481; 0054-2527; 72789-174; 82388-001; 46708-148; 50090-6052; 64117-256; 0054-0021; 68084-640; 70518-0904; 70518-1481; 0054-8527; 66039-947; 73309-248; 23155-763; 42291-496; 43063-901; 46708-304; 51079-180
UNII 2BMD2GNA4V
Synonyms Lithium Carbonate | Carbonate, Lithium | Dilithium Carbonate | Carbonate, Dilithium | Lithane | Lithium Bicarbonate | Bicarbonate, Lithium | Lithobid | Lithonate | CP-15,467-61 | CP 15,467 61 | CP15,46761 | Micalith | NSC-16895 | NSC 16895 | NSC16895 | Priadel | Quilinorm-retard | Quilinorm retard | Quilinormretard | Eskalith | Lithotabs
Chemical Information
Molecular Formula CLi2O3
CAS Registry Number 554-13-2
SMILES [Li+].[Li+].C(=O)([O-])[O-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Delirium19.13.02.0010.002409%
Dementia17.03.01.001; 19.20.02.0010.001338%-
Dental caries07.09.01.001--
Depressed level of consciousness17.02.04.0020.001071%
Depressed mood19.15.02.0010.001071%-
Dermatitis23.03.04.002---
Diabetes insipidus05.03.03.004; 14.05.07.0030.002409%-
Diarrhoea07.02.01.001--
Discomfort08.01.08.003---
Disorientation17.02.05.015; 19.13.01.0020.001606%-
Disturbance in attention17.03.03.001; 19.21.02.0020.001446%
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Drooling17.02.05.0050.000535%-
Drug interaction08.06.03.0010.002945%-
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dysarthria17.02.08.001; 19.19.03.0010.004926%
Dysgeusia07.14.03.001; 17.02.07.003--
Dyskinesia17.01.02.0060.001338%
Dyspepsia07.01.02.001--
Dysphonia17.02.08.004; 19.19.03.002; 22.12.03.006--
Dyspnoea02.11.05.003; 22.02.01.004--
Dystonia17.01.03.001---
Electrocardiogram normal13.14.05.022---
Electrocardiogram T wave inversion13.14.05.007---
Electroencephalogram abnormal13.07.03.001---
Electrolyte imbalance14.05.01.0020.000803%-
Encephalopathy17.13.02.0010.003587%
Enuresis19.07.04.001; 20.02.02.0030.001820%-
Epilepsy17.12.03.002---
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ADReCS-Target
Drug Name ADR Term Target
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