Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Levomilnacipran hydrochloride
Drug ID BADD_D01280
Description Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor. Chemically, levomilnacipran is the 1S,2R-enantiomer of milnacipran. FDA approved on July 25, 2013.
Indications and Usage Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor and is indicated for the treatment of major depressive disorder (MDD).
Marketing Status Prescription; Discontinued
ATC Code N06AX28
DrugBank ID DB08918
KEGG ID D10133
MeSH ID D000078862
PubChem ID 6917778
TTD Drug ID D02XOK
NDC Product Code 50370-0043; 0456-2213; 0456-2280; 0456-2212; 0456-2281; 69766-018; 0456-2241; 0456-2221; 0456-2202; 51604-1183; 53069-1090; 53069-1100; 0456-2240; 0456-2220
Synonyms Levomilnacipran | Fetzima | Levomilnacipran Hydrochloride
Chemical Information
Molecular Formula C15H23ClN2O
CAS Registry Number 101152-94-7
SMILES CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2.Cl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Aggression19.05.01.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Anger19.04.02.001--Not Available
Angina pectoris02.02.02.002; 24.04.04.002--
Angle closure glaucoma06.03.01.001--Not Available
Blood cholesterol increased13.12.01.002--
Blood pressure diastolic increased13.14.03.004--Not Available
Blood pressure increased13.14.03.005--Not Available
Blood pressure systolic increased13.14.03.006--Not Available
Bruxism07.01.06.008; 19.11.03.001--Not Available
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Conjunctival haemorrhage06.07.01.001; 24.07.05.001--Not Available
Constipation07.02.02.001--
Dermatitis23.03.04.002--Not Available
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Dizziness postural02.01.02.005; 17.02.05.004; 24.06.02.008--Not Available
Dry eye06.08.02.001--
Dry skin23.03.03.001--
Ejaculation delayed21.03.01.001--Not Available
Ejaculation disorder21.03.01.002--
Ejaculation failure21.03.01.003--Not Available
Epididymitis11.01.19.005; 21.09.02.001--Not Available
Extrapyramidal disorder17.01.02.007--
Eye disorder06.08.03.001--Not Available
Flatulence07.01.04.002--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Haematuria20.02.01.006; 24.07.01.047--
Haemorrhagic disorder01.01.03.004; 24.07.01.021--Not Available
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