Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Iotrolan
Drug ID BADD_D01185
Description Nonionic, isotonic contrast medium designed for intrathecal use.
Indications and Usage Not Available
Marketing Status approved
ATC Code V08AB06
DrugBank ID DB09487
KEGG ID D01714
MeSH ID C033300
PubChem ID 3738
TTD Drug ID D0B8LN
NDC Product Code Not Available
UNII 16FL47B687
Synonyms iotrolan | iotrol | Isovist | Isovist 300 | Osmovist | DL 3-117 | DL 3117 | DL-3-117
Chemical Information
Molecular Formula C37H48I6N6O18
CAS Registry Number 79770-24-4
SMILES CN(C1=C(C(=C(C(=C1I)C(=O)NC(CO)C(CO)O)I)C(=O)NC(CO)C(CO)O)I)C(=O)CC(=O)N(C)C2=C( C(=C(C(=C2I)C(=O)NC(CO)C(CO)O)I)C(=O)NC(CO)C(CO)O)I
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Acidosis14.01.03.002--
Agitation17.02.05.012; 19.06.02.001--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anoxia22.02.02.009---
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Arachnoiditis12.02.04.002; 17.06.01.001--
Back pain15.03.04.005--
Body temperature increased13.15.01.001---
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.001--
Cardio-respiratory arrest02.03.04.002; 22.02.06.007---
Cellulitis11.02.01.001; 23.11.02.004---
Chills08.01.09.001; 15.05.03.016--
Coma17.02.09.001---
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cyanosis02.11.04.004; 22.02.02.007; 23.06.04.005; 24.03.01.007--
Depressed level of consciousness17.02.04.002--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Ear pain04.03.01.003--
Epilepsy17.12.03.002---
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