Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Hemin
Drug ID BADD_D01058
Description Hemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.
Indications and Usage Used in the management of porphyria attacks, particularly in acute intermittent porphyria.
Marketing Status approved; investigational
ATC Code B06AB01
DrugBank ID DB03404
KEGG ID D10003
MeSH ID D006427
PubChem ID 26945
TTD Drug ID D0UU1I
NDC Product Code 55292-702; 51014-7945
UNII 743LRP9S7N
Synonyms Hemin | Ferriheme Chloride | Chloride, Ferriheme | Protohemin IX | Protohemin | Chlorohemin | Ferriprotoporphyrin IX Chloride | Chloride, Ferriprotoporphyrin IX | Ferrihaem | Panhematin | Ferriprotoporphyrin IX | Hematin | Alkaline Hematin D-575 | Alkaline Hematin D 575 | Hematin D-575, Alkaline | Ferriprotoporphyrin
Chemical Information
Molecular Formula C34H32FeN4O4
CAS Registry Number 14875-96-8
SMILES CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C) CCC(=O)O)CCC(=O)O.[Fe+2]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Infusion site extravasation08.02.05.007; 12.07.05.008-
Iron overload12.02.08.005; 14.13.03.002-
Acute kidney injury20.01.03.016--
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