Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Halobetasol
Drug ID BADD_D01051
Description Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047]
Indications and Usage For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Marketing Status Prescription; Discontinued
ATC Code D07AC21
DrugBank ID DB00596
KEGG ID D08660
MeSH ID C064466
PubChem ID 5311167
TTD Drug ID D00XPC
NDC Product Code Not Available
Synonyms halobetasol | ulobetasol | Ultravate | halobetasol propionate | 6 alpha-fluoroclobetasol 17-propionate | 6-fluoroclobetasol 17-propionate | CGP 14 458 | CGP-14458 | CGP 14458
Chemical Information
Molecular Formula C22H27ClF2O4
CAS Registry Number 98651-66-2
SMILES CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C)F
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Agranulocytosis01.02.03.001--Not Available
Akathisia17.01.02.002; 19.06.02.006--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anxiety19.06.02.002--
Breast engorgement18.08.02.001; 21.05.05.002--Not Available
Breast pain21.05.05.003--
Bronchospasm10.01.03.012; 22.03.01.004--
Cataract06.06.01.001--
Catatonia19.11.01.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Death08.04.01.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis acneiform23.02.01.004--
Dermatitis contact10.01.01.003; 12.03.01.040; 23.03.04.004--Not Available
Diarrhoea07.02.01.001--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dyspepsia07.01.02.001--
Dyspnoea02.01.03.002; 22.02.01.004--
Electrocardiogram abnormal13.14.05.001--Not Available
Electrocardiogram QT prolonged13.14.05.004--
Emotional disorder19.04.02.005--Not Available
Erythema23.03.06.001--Not Available
Euphoric mood19.04.02.006--
Extrapyramidal disorder17.01.02.007--
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