Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Halobetasol
Drug ID BADD_D01051
Description Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047]
Indications and Usage Ulobetasol cream and ointment are indicated in the treatment of inflammatory and pruritic corticosteroid responsive dermatoses.[L15047] Ulobetasol lotion is indicated in the treatment of plaque psoriasis.[L15052]
Marketing Status approved
ATC Code D07AC21
DrugBank ID DB00596
KEGG ID D08660
MeSH ID C064466
PubChem ID 5311167
TTD Drug ID D00XPC
NDC Product Code Not Available
UNII 9P6159HM7T
Synonyms halobetasol | ulobetasol | Ultravate | halobetasol propionate | 6 alpha-fluoroclobetasol 17-propionate | 6-fluoroclobetasol 17-propionate | CGP 14 458 | CGP-14458 | CGP 14458
Chemical Information
Molecular Formula C22H27ClF2O4
CAS Registry Number 98651-66-2
SMILES CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001---
Agitation17.02.05.012; 19.06.02.001--
Agranulocytosis01.02.03.001---
Akathisia17.01.02.002; 19.06.02.006--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anxiety19.06.02.002--
Breast engorgement18.08.02.001; 21.05.05.002---
Breast pain21.05.05.003--
Bronchospasm10.01.03.012; 22.03.01.004--
Cataract06.06.01.001--
Catatonia19.11.01.001---
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Death08.04.01.001--
Depression19.15.01.001--
Dermatitis23.03.04.002---
Dermatitis acneiform23.02.01.004--
Dermatitis contact10.01.01.003; 12.03.01.040; 23.03.04.004---
Diarrhoea07.02.01.001--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Electrocardiogram abnormal13.14.05.001---
Electrocardiogram QT prolonged13.14.05.004--
Emotional disorder19.04.02.005---
Erythema23.03.06.001---
Euphoric mood19.04.02.006--
Extrapyramidal disorder17.01.02.007--
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