Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fluorometholone
Drug ID BADD_D00929
Description A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Indications and Usage For the ophthalmic treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.
Marketing Status Prescription; Discontinued
ATC Code C05AA06; D07AB06; D07XB04; D10AA01; S01BA07; S01CB05
DrugBank ID DB00324
KEGG ID D01367
MeSH ID D005469
PubChem ID 9878
TTD Drug ID D0P0HT
NDC Product Code 22552-0050; 11980-211; 60758-880; 82298-120; 0023-0316; 46439-8770; 82298-119; 11980-228
Synonyms Fluorometholone | FML Liquifilm | PMS-Fluorometholone | PMS Fluorometholone | Cortisdin | Efflumidex | FML Forte | Flucon | Isopto Flucon | Flucon, Isopto | Fluor-Op | Fluor Op | Fluoro-Ophtal | Fluoro Ophtal | Fluoropos | FML
Chemical Information
Molecular Formula C22H29FO4
CAS Registry Number 426-13-1
SMILES CC1CC2C3CCC(C3(CC(C2(C4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Accommodation disorder06.02.04.001--Not Available
Agranulocytosis01.02.03.001--Not Available
Aplastic anaemia01.03.03.002--Not Available
Cataract06.06.01.001--
Cataract subcapsular06.06.01.002--Not Available
Conjunctivitis06.04.01.002; 11.01.06.012--
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Dysgeusia07.14.03.001; 17.02.07.003--
Endophthalmitis06.04.05.009; 11.01.06.003--
Erythema of eyelid06.04.04.003; 23.03.06.006--Not Available
Eye discharge06.04.05.001--Not Available
Eye disorder06.08.03.001--Not Available
Eye infection06.04.05.007; 11.01.06.001--
Eye infection bacterial06.04.05.013; 11.02.01.015--Not Available
Eye infection fungal06.04.05.020; 11.03.05.017--Not Available
Eye infection viral06.04.05.018; 11.05.04.022--Not Available
Eye irritation06.04.05.003--Not Available
Eye pain06.08.03.002--
Eye swelling06.08.03.003--Not Available
Eyelid oedema06.04.04.004; 10.01.05.001; 23.04.01.003--Not Available
Eyelid ptosis06.05.01.002; 17.17.02.004--Not Available
Glaucoma06.03.01.002--
Hepatic necrosis09.01.07.002--
Hyperadrenocorticism05.01.01.003; 14.11.01.009; 24.08.02.005--Not Available
Hypercorticoidism05.01.01.004; 14.11.01.017; 24.08.04.002--Not Available
Hypersensitivity10.01.03.003--
Impaired healing08.03.02.001--Not Available
Instillation site pain08.02.01.008; 12.07.01.008--Not Available
Intraocular pressure increased13.07.04.002--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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