Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ferumoxytol non-stoichiometric magnetite
Drug ID BADD_D00890
Description Ferumoxytol is an intravenously administered iron preparation indicated in the EU and the US for the treatment of iron deficiency anemia in adult patients with chronic kidney disease (CKD) [A32478]. It is comprised of superparamagnetic iron oxide nanoparticles which are coated by a semi-synthetic carbohydrate shell in an isotonic, neutral pH solution that may be administered at relatively high dose by rapid intravenous injection [L2181].
Indications and Usage This drug is indicated for the treatment of iron deficiency anemia in adult patients who have experienced intolerance to oral iron or have experienced an unsatisfactory response to oral iron or who have chronic kidney disease (CKD) [FDA label].
Marketing Status approved; investigational
ATC Code Not Available
DrugBank ID DB06215
KEGG ID D04177; D09142
MeSH ID D052203
PubChem ID 6432052
TTD Drug ID D06CTM
NDC Product Code 63552-026
UNII CLH5FT6412
Synonyms Ferrosoferric Oxide | Oxide, Ferrosoferric | Ferriferrous Oxide | Oxide, Ferriferrous | Magnetite | Feraheme | Ferumoxytol
Chemical Information
Molecular Formula Fe3O4
CAS Registry Number 119683-68-0
SMILES [O-2].[O-2].[O-2].[O-2].[Fe+2].[Fe+3].[Fe+3]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Face oedema08.01.07.003; 10.01.05.002; 23.04.01.004-
Feeling abnormal08.01.09.014--
Feeling cold08.01.09.008--
Feeling hot08.01.09.009--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002-
Gastrooesophageal reflux disease07.02.02.003-
Headache17.14.01.001-
Hyperhidrosis08.01.03.028; 23.02.03.004-
Hypersensitivity10.01.03.003-
Hypertension24.08.02.001-
Hypoaesthesia17.02.06.023; 23.03.03.081--
Hypotension24.06.03.002-
Hypoxia22.02.02.003-
Injection site bruising08.02.03.042; 12.07.03.042; 23.03.11.015; 24.07.06.017--
Injection site extravasation08.02.03.002; 12.07.03.002--
Lethargy08.01.01.008; 17.02.04.003; 19.04.04.004-
Lip swelling07.05.04.005; 10.01.05.005; 23.04.01.007--
Loss of consciousness17.02.04.004--
Malaise08.01.01.003-
Moaning08.01.03.094; 19.04.02.011--
Muscle contractions involuntary15.05.03.008; 17.05.03.001--
Muscle spasms15.05.03.004-
Nasal congestion22.04.04.001-
Nausea07.01.07.001-
Neck pain15.03.04.009-
Oedema08.01.07.006; 14.05.06.010---
Oedema peripheral02.05.04.007; 08.01.07.007; 14.05.06.011--
Pain in extremity15.03.04.010-
Pallor08.01.03.032; 23.03.03.031; 24.03.04.001--
Palpitations02.11.04.012-
The 2th Page    First    Pre   2 3 4    Next   Last    Total 4 Pages