Drug Name |
Disulfiram |
Drug ID |
BADD_D00695 |
Description |
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. |
Indications and Usage |
For the treatment and management of chronic alcoholism |
Marketing Status |
approved |
ATC Code |
N07BB01; P03AA04 |
DrugBank ID |
DB00822
|
KEGG ID |
D00131
|
MeSH ID |
D004221
|
PubChem ID |
3117
|
TTD Drug ID |
D0X5SD
|
NDC Product Code |
42973-137; 71052-221; 42794-028; 0054-0357; 73309-150; 51927-3121; 62135-432; 64980-171; 0054-0356; 38779-1971; 65571-0005; 62135-431; 64980-172; 51927-0188; 72643-028; 47781-607; 60429-196 |
UNII |
TR3MLJ1UAI
|
Synonyms |
Disulfiram | Bis(diethylthiocarbamoyl) Disulfide | Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2 | Tetraethylthiuram Disulfide | Disulfide, Tetraethylthiuram | Antabus | Antabuse | Teturam | Dicupral | Esperal | Alcophobin | Anticol |