ADR Ontology |
ADR Term |
Wernicke's encephalopathy |
ADR ID |
BADD_A07834 |
ADR Hierarchy |
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Description |
An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. THIAMINE DEFICIENCY and chronic ALCOHOLISM are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to KORSAKOFF SYNDROME. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3) [MeSH] |
MedDRA Code |
10047911 |
MeSH ID |
D014899
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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Synonym |
Wernicke's encephalopathy | Wernicke's syndrome | Wernicke Encephalopathy | Encephalopathies, Wernicke | Wernicke Encephalopathies | Wernicke's Encephalopathy | Beriberi, Cerebral | Cerebral Beriberi | Encephalopathy, Wernicke | Encephalopathy, Gayet-Wernicke | Encephalopathy, Gayet Wernicke | Encephalopathy, Wernicke's | Encephalopathy, Wernickes | Wernicke Superior Hemorrhagic Polioencephalitis | Gayet-Wernicke Encephalopathy | Gayet Wernicke Encephalopathy | Wernicke Syndrome | Wernicke Disease | Wernicke Polioencephalitis, Superior Hemorrhagic | Wernicke's Disease | Wernicke's Superior Hemorrhagic Polioencephalitis | Wernicke's Syndrome | Wernicke's Polioencephalitis, Superior Hemorrhagic |
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Drugs Leading to the ADR |
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