Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dexmethylphenidate hydrochloride
Drug ID BADD_D00631
Description Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 2002[A177181]. It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant[A177193]. It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181]. The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or the racemic mixture[A177181].
Indications and Usage Dexmethylphenidate is used as a treatment for ADHD, ideally in conjunction with psychological, educational, behavioral or other forms of treatment[A177187,Label].
Marketing Status approved; investigational
ATC Code N06BA11
DrugBank ID DB06701
KEGG ID D03721
MeSH ID D064699
PubChem ID 154100
TTD Drug ID D02QCD
NDC Product Code 0781-2686; 11014-0316; 60274-710; 0078-0382; 0115-1684; 43602-332; 43602-333; 49884-048; 49884-539; 57664-379; 57664-622; 57664-624; 70010-009; 0527-8106; 0781-2688; 10702-108; 16714-567; 27808-091; 27808-093; 0115-1682; 42858-225; 43386-862; 43602-327; 57664-626; 63629-2175; 63629-2177; 63629-9469; 70010-005; 72162-1472; 72162-1503; 0781-2687; 11014-0314; 60274-720; 10702-107; 0078-0381; 0078-0431; 0078-0432; 0078-0433; 0093-5562; 42858-410; 43602-330; 43602-331; 57664-378; 63629-2173; 63629-2174; 70010-008; 70010-010; 70010-011; 57664-629; 0527-8109; 0527-8110; 0527-8111; 72162-1502; 53834-201; 0078-0609; 16714-566; 0093-5046; 0093-5553; 27808-092; 31722-229; 0115-1683; 0115-1685; 0115-1709; 49884-090; 57664-376; 57664-625; 72162-1493; 0781-2684; 11014-0080; 11014-0211; 11014-0213; 31722-234; 31722-236; 49884-248; 63629-2176; 63629-2178; 63629-2306; 63629-2307; 67877-655; 67877-656; 70010-007; 0527-8113; 72162-1473; 72162-1507; 0781-2683; 0781-2685; 60274-730; 16714-568; 43602-334; 57664-628; 63629-2172; 63629-9467; 70010-006; 0527-8108; 72162-1496; 11014-0103; 11014-0212; 60274-705; 0078-0434; 0078-0493; 0093-5550; 0115-9918; 0115-9920; 42858-011; 43602-328; 49884-333; 67877-657; 0527-8107; 0781-2682; 0781-2689; 17180-1725; 0078-0380; 0078-0430; 0093-5552; 0115-9921; 0115-9922; 43386-861; 43602-329; 49884-339; 49884-546; 57664-623; 63629-2305; 70010-004; 11014-0317; 10702-106; 16714-562; 0093-5045; 31722-230; 31722-233; 0115-1686; 0115-1710; 0115-9919; 43386-860; 63629-2171; 63629-9468; 0527-8112; 72162-1488; 0792-0619; 11014-0315; 11014-0318; 60274-715; 60274-725; 60274-735; 60274-740; 0078-0608; 16714-563; 16714-564; 16714-565; 16714-569; 0093-5551; 0093-5554; 31722-231; 31722-232; 31722-235; 49884-049; 57664-621
UNII 1678OK0E08
Synonyms Dexmethylphenidate Hydrochloride | Hydrochloride, Dexmethylphenidate | Focalin XR | XR, Focalin | Dexmethylphenidate | Focalin
Chemical Information
Molecular Formula C14H20ClNO2
CAS Registry Number 19262-68-1
SMILES COC(=O)C(C1CCCCN1)C2=CC=CC=C2.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Aggression19.05.01.001---
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Angina pectoris02.02.02.002; 24.04.04.002--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anxiety19.06.02.002--
Arrhythmia02.03.02.001---
Arthralgia15.01.02.001--
Blood pressure increased13.14.03.005---
Body temperature increased13.15.01.001---
Cerebral arteritis17.08.02.004; 24.12.02.002---
Coma hepatic09.01.03.005; 17.02.09.002---
Depressed mood19.15.02.001---
Depression19.15.01.001--
Dermatitis23.03.04.002---
Dermatitis exfoliative10.01.01.004; 23.03.07.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Drug interaction08.06.03.001---
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dyspepsia07.01.02.001--
Erythema multiforme10.01.03.015; 23.03.01.003--
Feeling jittery08.01.09.016---
Gastrointestinal disorder07.11.01.001---
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Hepatic function abnormal09.01.02.001---
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