Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dexmedetomidine hydrochloride
Drug ID BADD_D00630
Description An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Indications and Usage For sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; anxiety reduction and analgesia
Marketing Status approved; vet_approved
ATC Code N05CM18
DrugBank ID DB00633
KEGG ID D01205
MeSH ID D020927
PubChem ID 6918081
TTD Drug ID D0U3DU
NDC Product Code 66583-0510; 51224-215; 0409-4596; 71872-7031; 50711-0008; 43066-565; 68094-247; 50384-0100; 42023-186; 42023-187; 44567-602; 0338-9557; 66794-235; 68094-147; 70771-1319; 71225-133; 57664-596; 63323-421; 0409-2815; 70121-1389; 71225-126; 71872-7122; 72572-128; 12780-4640; 44567-601; 51224-115; 67457-924; 72572-127; 57884-0024; 43598-975; 44567-600; 0409-0155; 0409-1454; 14593-887; 42023-146; 43598-976; 44567-603; 51224-015; 67457-925; 68083-238; 68083-239; 0409-1174; 56087-0001; 56087-0002; 72015-001; 0143-9525; 0338-9555; 66794-234; 68094-047; 0409-1434; 0409-1638; 68382-124; 70121-1388; 71225-132; 52952-006; 17478-055; 0143-9526; 43066-561; 63323-671; 0404-9938; 0409-1660; 0409-3301; 71872-7030; 52584-638
UNII 1018WH7F9I
Synonyms Dexmedetomidine | MPV-1440 | MPV 1440 | MPV1440 | Precedex | Dexmedetomidine Hydrochloride | Hydrochloride, Dexmedetomidine
Chemical Information
Molecular Formula C13H17ClN2
CAS Registry Number 145108-58-3
SMILES CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pleural effusion22.05.02.002--
Pulmonary congestion02.05.02.002; 22.01.03.002; 24.03.08.001---
Pulmonary oedema02.05.02.003; 22.01.03.003--
Pyrexia08.05.02.003--
Respiratory depression17.02.05.047; 22.02.01.010---
Respiratory failure14.01.04.003; 22.02.06.002--
Seizure17.12.03.001--
Sinus tachycardia02.03.03.010--
Speech disorder17.02.08.003; 19.19.02.002; 22.12.03.027---
Systolic hypertension24.08.02.007---
Tachycardia02.03.02.007---
Thirst08.01.09.021; 14.03.02.007---
Ventricular arrhythmia02.03.04.006--
Ventricular tachycardia02.03.04.010--
Visual impairment06.02.10.013---
Vomiting07.01.07.003--
Wheezing22.03.01.009--
Post procedural haemorrhage12.02.05.004; 24.07.01.014--
Haemorrhage24.07.01.002---
Urine output decreased13.13.03.001--
Cardiac disorder02.11.01.003---
Supraventricular tachyarrhythmia02.03.03.014---
Acute kidney injury20.01.03.016--
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