Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dexmedetomidine
Drug ID BADD_D00629
Description An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Indications and Usage For sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; anxiety reduction and analgesia
Marketing Status approved; vet_approved
ATC Code N05CM18
DrugBank ID DB00633
KEGG ID D00514
MeSH ID D020927
PubChem ID 5311068
TTD Drug ID D0U3DU
NDC Product Code 55150-209; 81092-1180; 16729-432; 68083-527; 81092-1120; 67457-251; 70860-605; 66794-230; 66794-238; 62068-308; 16729-239; 71288-505; 66794-233; 71872-7150
UNII 67VB76HONO
Synonyms Dexmedetomidine | MPV-1440 | MPV 1440 | MPV1440 | Precedex | Dexmedetomidine Hydrochloride | Hydrochloride, Dexmedetomidine
Chemical Information
Molecular Formula C13H16N2
CAS Registry Number 113775-47-6
SMILES CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Acidosis14.01.03.002--
Acute respiratory distress syndrome10.02.01.067; 22.01.03.001; 24.03.02.034--
Agitation17.02.05.012; 19.06.02.0010.000418%
Alanine aminotransferase increased13.03.04.005--
Anaemia01.03.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.0060.000196%
Anaphylactic shock10.01.07.002; 24.06.02.0040.000261%-
Anxiety19.06.02.002--
Apnoea22.02.01.0010.000131%
Arrhythmia02.03.02.0010.000196%-
Arteriospasm coronary02.02.02.005; 12.02.01.031; 24.04.04.0050.002287%-
Aspartate aminotransferase increased13.03.04.011--
Aspiration22.02.07.0070.000131%
Atelectasis22.01.02.0010.000392%
Atrial fibrillation02.03.03.0020.000131%
Atrioventricular block02.03.01.0020.000196%-
Atrioventricular block complete02.03.01.0030.000392%
Atrioventricular block first degree02.03.01.0040.000131%
Blood pressure fluctuation24.06.01.002---
Blood urea increased13.13.01.006---
Body temperature decreased13.15.01.010---
Body temperature increased13.15.01.001---
Bradycardia02.03.02.0020.003254%-
Bronchospasm10.01.03.012; 22.03.01.004--
Carbon dioxide increased13.02.01.011---
Cardiac arrest02.03.04.0010.001503%
Cardiac failure02.05.01.0010.000131%
Cardiac output decreased13.14.02.001---
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