Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cerebral artery occlusion17.08.01.028; 24.04.06.0200.004037%-
Cerebral atrophy17.11.01.0010.000367%-
Cerebral haemorrhage17.08.01.003; 24.07.04.0010.059452%-
Cerebral infarction17.08.01.004; 24.04.06.0020.035280%-
Cerebral ischaemia17.08.01.005; 24.04.06.0030.005260%
Cerebral thrombosis17.08.01.006; 24.01.04.0030.001346%-
Cerebral venous thrombosis17.08.03.002; 24.01.04.0050.000489%-
Cerebrovascular accident17.08.01.007; 24.03.05.0010.212166%
Cerebrovascular disorder17.08.02.002; 24.03.05.0020.002202%-
Cholangiocarcinoma09.04.02.009; 16.07.01.0020.000245%-
Cholangitis09.02.01.0020.001223%-
Cholecystitis09.03.01.0010.002740%
Cholecystitis acute09.03.01.0030.002814%-
Circulatory collapse24.06.02.0010.002691%-
Clonus17.02.05.0020.000367%-
Coagulopathy01.01.02.0010.019230%-
Colitis ischaemic07.08.01.004; 24.04.08.0120.002447%-
Colon cancer07.21.01.001; 16.13.01.0010.007340%-
Coma17.02.09.0010.006606%-
Compartment syndrome15.05.05.005; 24.04.05.0060.000979%-
Conjunctival haemorrhage06.07.01.001; 24.07.05.0010.001639%-
Cor pulmonale02.05.03.001; 22.06.01.003; 24.08.03.0010.000245%-
Coronary artery disease02.02.01.001; 24.04.04.0060.001957%-
Coronary artery occlusion02.02.01.006; 12.02.01.036; 24.04.04.0130.001835%-
Coronary artery stenosis02.02.01.010; 12.02.01.037; 24.04.04.0170.000612%-
Coronary artery thrombosis02.02.01.007; 24.01.05.0020.000856%-
Cutaneous vasculitis10.02.02.003; 23.06.02.001; 24.12.04.0080.000734%-
Cystitis haemorrhagic20.03.02.0030.000367%-
Decubitus ulcer23.03.11.0060.000979%-
Defaecation urgency07.02.04.0010.000367%-
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