Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cor pulmonale
ADR ID BADD_A01074
ADR Hierarchy
02      Cardiac disorders
02.05      Heart failures
02.05.03      Right ventricular failures
02.05.03.001      Cor pulmonale
22      Respiratory, thoracic and mediastinal disorders
22.06      Pulmonary vascular disorders
22.06.01      Pulmonary hypertensions
22.06.01.003      Cor pulmonale
24      Vascular disorders
24.08      Vascular hypertensive disorders
24.08.03      Pulmonary hypertensions
24.08.03.001      Cor pulmonale
Description Hypertrophy and dilation of the RIGHT VENTRICLE of the heart that is caused by PULMONARY HYPERTENSION. This condition is often associated with pulmonary parenchymal or vascular diseases, such as CHRONIC OBSTRUCTIVE PULMONARY DISEASE and PULMONARY EMBOLISM. [MeSH]
MedDRA Code 10010968
MeSH ID D011660
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cor pulmonale | Cor pulmonale NOS | Disease heart pulmonary | Heart disease pulmonary | Pulmonary Heart Disease | Heart Disease, Pulmonary | Heart Diseases, Pulmonary | Disease, Pulmonary Heart | Cor Pulmonale | Diseases, Pulmonary Heart | Pulmonary Heart Diseases
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00100Ambrisentan0.000963%
BADD_D00151Apixaban0.000043%
BADD_D00194Azacitidine0.000112%
BADD_D00285Bosentan0.000963%
BADD_D00563Dabigatran0.000245%
BADD_D00589Dasatinib--
BADD_D00711Dornase alfa--
BADD_D01135Iloprost0.000206%
BADD_D01250Lasofoxifene--
BADD_D01336Macitentan0.000602%
BADD_D01835Pregabalin--
BADD_D01942Riluzole--
BADD_D01948Riociguat0.000241%
BADD_D02106Tadalafil0.000195%
BADD_D02268Treprostinil0.000247%
BADD_D02337Varenicline--
BADD_D02338Varenicline tartrate--
BADD_D02443Tiotropium0.000057%
BADD_D02470Nintedanib0.000224%
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