Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cyclo-upup
Drug ID BADD_D00544
Description Not Available
Indications and Usage Not Available
Marketing Status Not Available
ATC Code Not Available
DrugBank ID Not Available
KEGG ID Not Available
MeSH ID C036198
PubChem ID 194491
TTD Drug ID Not Available
NDC Product Code Not Available
UNII Not Available
Synonyms bis(3'-5')cyclic diuridine monophosphate | cyclic bis((3'-5')uridylic acid) | cyclo-UpUp | cyclo(uridylyl-(3'-5')uridine monophosphate)
Chemical Information
Molecular Formula C18H22N4O16P2
CAS Registry Number 73120-97-5
SMILES C1C2C(C(C(O2)N3C=CC(=O)NC3=O)O)OP(=O)(OCC4C(C(C(O4)N5C=CC(=O)NC5=O)O)OP(=O)(O1)O )O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypertension24.08.02.001--
Hypervolaemia02.05.04.019; 14.05.06.003---
Hypocalcaemia14.04.01.004--
Hypophosphataemia14.04.03.001--
Hypotension24.06.03.002--
Injection site irritation08.02.03.027; 12.07.03.027---
Injection site pain08.02.03.010; 12.07.03.011---
Injection site reaction08.02.03.014; 12.07.03.015--
Laryngeal pain22.12.03.010--
Methaemoglobinaemia01.05.01.002--
Mucosal inflammation08.01.06.002---
Myocardial ischaemia02.02.02.008; 24.04.04.010---
Nausea07.01.07.001--
Nervous system disorder17.02.10.001---
Oedema peripheral02.05.04.007; 08.01.07.007; 14.05.06.011--
Pain08.01.08.004--
Pharyngitis07.05.07.004; 11.01.13.003; 22.07.03.004--
Pulmonary haemorrhage22.12.01.009; 24.07.01.016--
Rash23.03.13.001---
Respiratory failure14.01.04.003; 22.02.06.002--
Rhinitis11.01.13.004; 22.07.03.006--
Sepsis11.01.11.003--
Thrombocytopenia01.08.01.002---
Tumour lysis syndrome14.05.01.004; 16.32.03.002--
Urticaria10.01.06.001; 23.04.02.001--
Vomiting07.01.07.003--
Musculoskeletal discomfort15.03.04.001---
Blood disorder01.05.01.004---
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