ADReCS

Pharmaceutical Information

Drug Name	Cefuroxime
Drug ID	BADD_D00407
Description	Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage	For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status	approved
ATC Code	J01DC02; S01AA27
DrugBank ID	DB01112
KEGG ID	D00262
MeSH ID	D002444
PubChem ID	41375
TTD Drug ID	D0Y2IE
NDC Product Code	0143-9567; 0143-9569; 0143-9976; 0143-9568; 0143-9977; 0143-9979
UNII	O1R9FJ93ED
Synonyms	Cefuroxime \| Cephuroxime \| Zinacef \| Ketocef

Chemical Information

Molecular Formula	C16H16N4O8S
CAS Registry Number	55268-75-2
SMILES	CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Blood urea increased	13.13.01.006	-	-	-
Body temperature increased	13.15.01.001	-	-	-
Bradycardia	02.03.02.002	0.000429%		-
Brain hypoxia	17.08.02.009; 22.02.02.010; 24.04.06.022	0.000286%		-
Bronchitis	11.01.09.001; 22.07.01.001	-	-
Bronchospasm	10.01.03.012; 22.03.01.004	0.000644%
Burning sensation	08.01.09.029; 17.02.06.001	0.000286%		-
Capillary leak syndrome	08.01.07.012; 24.06.03.001	0.000143%
Cardiac arrest	02.03.04.001	0.001359%
Cardio-respiratory arrest	02.03.04.002; 22.02.06.007	0.000215%		-
Cardiovascular disorder	02.11.01.010; 24.03.02.009	0.000501%		-
Chest discomfort	02.02.02.009; 08.01.08.019; 22.12.02.002	0.000501%		-
Chest pain	02.02.02.011; 08.01.08.002; 22.12.02.003	0.000858%		-
Chills	08.01.09.001; 15.05.03.016	0.000672%
Cholelithiasis	09.03.01.002	0.000143%		-
Cholestasis	09.01.01.001	0.000143%		-
Circulatory collapse	24.06.02.001	0.000501%		-
Cold sweat	08.01.03.024; 23.02.03.002	0.000215%		-
Colitis	07.08.01.001	-	-
Colitis ischaemic	07.08.01.004; 24.04.08.012	0.000215%		-
Colour blindness acquired	06.02.09.002	0.001946%		-
Coma	17.02.09.001	0.000286%		-
Complications of transplanted liver	09.01.08.011; 12.02.09.014	-	-	-
Confusional state	17.02.03.005; 19.13.01.001	-	-
Conjunctival haemorrhage	06.07.01.001; 24.07.05.001	0.000286%		-
Conjunctival oedema	06.04.01.001	0.000315%		-
Corneal deposits	06.06.03.002	0.000286%		-
Corneal oedema	06.04.02.001	0.006724%		-
Corneal opacity	06.06.03.005	0.001860%		-
Coronary artery stenosis	02.02.01.010; 12.02.01.037; 24.04.04.017	0.000143%		-

The 2th Page First Pre 2 3 4 5 6 Next Last Total 13 Pages