Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Carbamazepine
Drug ID BADD_D00356
Description Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965.[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1.[L1335] Interestingly, carbamazepine was the first anticonvulsant used to treat individuals with bipolar disorder.[A180319]
Indications and Usage For the treatment of epilepsy and pain associated with true trigeminal neuralgia.
Marketing Status Prescription; Discontinued
ATC Code N03AF01
DrugBank ID DB00564
KEGG ID D00252
MeSH ID D002220
PubChem ID 2554
TTD Drug ID D04MSM
NDC Product Code 60687-594; 51672-4123; 70518-3174; 67296-1637; 0781-5988; 68094-008; 0078-0509; 16571-682; 68084-561; 50090-5740; 68084-562; 0121-1894; 75834-221; 63629-8753; 70518-0181; 0904-7116; 68788-7825; 71335-0461; 51672-4047; 60505-2807; 60429-032; 50090-0384; 68071-4313; 0904-6172; 48087-0051; 70518-1769; 75834-220; 70518-2456; 68382-555; 42419-014; 29033-004; 30698-421; 16571-681; 16714-063; 0781-5987; 38779-0114; 50268-171; 70518-1433; 72189-157; 51927-2176; 54092-172; 13668-268; 51672-4124; 71930-072; 51552-0653; 70518-3176; 54092-173; 0615-3505; 0078-0508; 51672-4149; 35561-355; 65344-0028; 70518-1545; 0093-0090; 16714-065; 68382-557; 43063-328; 68788-7210; 0078-0512; 71930-073; 70518-3335; 68382-556; 71335-1730; 29033-019; 67386-621; 70518-3146; 70518-1436; 0781-8016; 51407-215; 49452-1705; 0832-6023; 43353-953; 70518-3266; 16714-064; 55154-1396; 76003-0251; 0078-0511; 0615-8125; 66993-409; 60505-2805; 60429-934; 51672-4150; 0093-0778; 17856-0407; 72664-218; 66993-407; 70518-2426; 51672-4151; 0832-6024; 63629-8255; 50090-2161; 70771-1469; 62512-0024; 70966-0020; 68094-007; 16571-680; 70518-2489; 60687-479; 70771-1470; 71205-025; 48087-0052; 35561-357; 51672-4005; 0121-1724; 13668-271; 60432-129; 71610-336; 60687-583; 63629-8743; 0121-0947; 70518-2841; 62991-1027; 35561-356; 0093-0109; 30698-419; 0904-6885; 70518-2653; 71930-074; 63552-060; 50090-4443; 63629-8721; 65372-1102; 71335-0691; 66993-408; 54092-171; 70771-1468; 63629-8720; 70518-2242; 0832-6022; 60505-0183; 60505-2806; 58118-0268; 0078-0510; 63629-8715; 51672-4041; 71335-0462; 50268-170; 29033-020; 0121-0862; 70518-0902; 50268-172; 0904-3854; 51672-4125; 30698-423
Synonyms Carbamazepine | Carbamazepine Acetate | Carbamazepine Dihydrate | Carbamazepine Hydrochloride | Carbamazepine L-Tartrate (4:1) | Carbamazepine Anhydrous | Carbamazepine Sulfate (2:1) | Carbazepin | Epitol | Finlepsin | Neurotol | Tegretol | Amizepine | Carbamazepine Phosphate
Chemical Information
Molecular Formula C15H12N2O
CAS Registry Number 298-46-4
SMILES C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Asphyxia12.01.08.011; 22.02.02.0010.000549%Not Available
Aspiration22.02.07.0070.000220%
Asterixis09.01.03.004; 17.01.06.0010.001684%Not Available
Asthenia08.01.01.0010.028625%Not Available
Asthma10.01.03.010; 22.03.01.002--Not Available
Ataxia08.01.02.004; 17.02.02.0010.018943%
Atelectasis22.01.02.0010.000842%
Atrial fibrillation02.03.03.002--
Atrial septal defect02.04.02.009; 03.07.02.0020.005052%Not Available
Atrioventricular block02.03.01.0020.001263%Not Available
Atrioventricular block complete02.03.01.0030.001263%
Atrioventricular block second degree02.03.01.0050.002526%
Attention deficit/hyperactivity disorder19.21.04.0010.002105%Not Available
Auditory disorder04.02.03.002--Not Available
Aura17.02.07.0110.001263%Not Available
Autism17.03.05.001; 19.22.02.0010.003789%Not Available
Autoimmune hepatitis09.01.07.019; 10.04.09.0010.000842%Not Available
Azotaemia20.01.01.0010.000842%Not Available
B-cell lymphoma01.15.01.001; 16.28.01.0010.000329%Not Available
Back pain15.03.04.005--
Bacteraemia11.01.11.0010.000842%
Bezoar07.11.01.0080.001684%Not Available
Bipolar I disorder19.16.01.0020.001684%Not Available
Blindness06.02.02.001; 17.17.01.0030.004210%Not Available
Blindness unilateral06.02.02.009; 17.17.01.0160.000842%Not Available
Blister12.01.06.002; 23.03.01.0010.021469%Not Available
Blood albumin decreased13.09.01.0010.000842%Not Available
Blood bilirubin increased13.03.01.0080.003789%
Blood calcium decreased13.11.01.0020.001263%Not Available
Blood cholesterol increased13.12.01.0020.002526%
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ADReCS-Target
Drug Name ADR Term Target
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