Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Butorphanol
Drug ID BADD_D00324
Description A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Indications and Usage For the relief of moderate to severe pain.
Marketing Status approved; illicit; vet_approved
ATC Code N02AF01
DrugBank ID DB00611
KEGG ID D03197
MeSH ID D002077
PubChem ID 5361092
TTD Drug ID D0X9RG
NDC Product Code 60592-917
UNII QV897JC36D
Synonyms Butorphanol | 17-(Cyclobutylmethyl)morphinan-3,14-diol | BC-2627 | BC 2627 | BC2627 | Beforal | Butorphanol Tartrate | Moradol | Stadol | Stadol NS | Torbugesic | Apo-Butorphanol | Dolorex
Chemical Information
Molecular Formula C21H29NO2
CAS Registry Number 42408-82-2
SMILES C1CCC2(C3CC4=C(C2(C1)CCN3CC5CCC5)C=C(C=C4)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rash23.03.13.001---
Respiratory disorder22.02.07.002---
Respiratory failure14.01.04.003; 22.02.06.002--
Rhinitis11.01.13.004; 22.07.03.006--
Seizure17.12.03.001--
Shock24.06.02.002---
Sinus congestion22.04.06.001---
Sinusitis11.01.13.005; 22.07.03.007--
Somnolence17.02.04.006; 19.02.05.003--
Stupor17.02.04.007; 19.02.05.004---
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Tachycardia02.03.02.007---
Tension19.06.02.005---
Therapeutic response decreased08.06.01.016---
Thinking abnormal17.02.05.023; 19.10.03.001---
Thirst08.01.09.021; 14.03.02.007---
Tinnitus04.04.01.002; 17.04.07.004--
Tremor17.01.06.002--
Upper respiratory tract infection11.01.13.009; 22.07.03.011--
Urticaria10.01.06.001; 23.04.02.001--
Vertigo04.04.01.003; 17.02.12.002--
Vision blurred06.02.06.007; 17.17.01.010--
Visual impairment06.02.10.013---
Vomiting07.01.07.003--
Withdrawal syndrome08.06.02.012; 19.07.06.023---
Hypoacusis04.02.01.006--
Rhinalgia22.12.03.020---
Sticky skin23.03.03.019---
Nasal discomfort22.12.03.012---
Vasodilation procedure25.03.01.001---
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