Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alendronic acid
Drug ID BADD_D00066
Description Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.
Marketing Status Prescription; Discontinued
ATC Code M05BA04
DrugBank ID DB00630
KEGG ID D07119
MeSH ID D019386
PubChem ID 2088
TTD Drug ID D09KLR
NDC Product Code Not Available
Synonyms Alendronate | 4-Amino-1-Hydroxybutylidene 1,1-Biphosphonate | Aminohydroxybutane Bisphosphonate | MK-217 | MK 217 | MK217 | Alendronate Monosodium Salt, Trihydrate | Alendronate Sodium | Fosamax
Chemical Information
Molecular Formula C4H13NO7P2
CAS Registry Number 66376-36-1
SMILES C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood bilirubin increased13.03.01.008--
Blood calcium decreased13.11.01.0020.001414%Not Available
Blood calcium increased13.11.01.0030.001010%Not Available
Blood cholesterol13.12.01.0140.000202%Not Available
Blood cholesterol increased13.12.01.0020.015559%
Blood cortisol decreased13.10.09.0040.000202%Not Available
Blood creatine phosphokinase increased13.04.01.001--
Blood creatinine increased13.13.01.004--
Blood glucose abnormal13.02.02.0080.000606%Not Available
Blood glucose decreased13.02.02.0010.000404%Not Available
Blood glucose increased13.02.02.0020.001718%Not Available
Blood iron decreased13.11.01.0060.000404%Not Available
Blood lactate dehydrogenase increased13.04.02.002--
Blood magnesium decreased13.11.01.0080.000505%Not Available
Blood parathyroid hormone increased13.10.07.0020.000505%Not Available
Blood potassium decreased13.11.01.0100.001313%Not Available
Blood potassium increased13.11.01.0110.000505%Not Available
Blood pressure abnormal13.14.03.0010.000303%Not Available
Blood pressure decreased13.14.03.002--Not Available
Blood pressure increased13.14.03.0050.002930%Not Available
Blood sodium decreased13.11.01.0120.000303%Not Available
Blood sodium increased13.11.01.0130.000202%Not Available
Blood thyroid stimulating hormone decreased13.10.03.0110.000202%Not Available
Blood thyroid stimulating hormone increased13.10.03.0060.000202%
Blood triglycerides increased13.12.03.0010.001010%Not Available
Blood urea increased13.13.01.0060.000404%Not Available
Body temperature increased13.15.01.0010.000505%Not Available
Bone development abnormal15.02.04.0030.000202%Not Available
Bone disorder15.02.04.0040.039202%Not Available
Bone neoplasm15.09.02.001; 16.29.01.0010.000202%Not Available
The 4th Page    First    Pre   4 5 6 7 8    Next   Last    Total 49 Pages