Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acyclovir sodium
Drug ID BADD_D00040
Description Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis[L7303,L7315,L7318,L7321,L7324,L7327]. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old.[L7321] Acyclovir was granted FDA approval on 29 March 1982.[L7318]
Indications and Usage For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox.
Marketing Status Prescription; Discontinued
ATC Code D06BB03; J05AB01; S01AD03
DrugBank ID DB00787
KEGG ID D02764
MeSH ID D000212
PubChem ID 23665721
TTD Drug ID D0B5MP
NDC Product Code 63323-325; 55150-155; 46014-1019; 55150-154; 14335-150
Synonyms Acyclovir | 9-((2-Hydroxyethoxy)methyl)guanine | Aciclovir | Acycloguanosine | Herpoviric | Aciclobeta | Aciclostad | Isavir | Laciken | Mapox | Maynar | Milavir | Opthavir | Supraviran | Viclovir | Vipral | Virax-Puren | Virax Puren | ViraxPuren | Virherpes | Virmen | Virolex | Virupos | Virzin | Wellcome-248U | Wellcome 248U | Wellcome248U | Zoliparin | Zovirax | Zyclir | Aciclovir Alonga | Alonga, Aciclovir | Acifur | Acipen Solutab | Solutab, Acipen | Acivir | Activir | Acyclo-V | Acyclo V | Acyclovir Sodium | Sodium, Acyclovir | Antiherpes Creme | aciclovir von ct | Avirax | Cicloferon | Clonorax | Cusiviral | Genvir | Herpetad | Herpofug | Herpotern | Aci-Sanorania | Aci Sanorania | Aciclovir-Sanorania | Aciclovir Sanorania | Acic
Chemical Information
Molecular Formula C8H10N5NaO3
CAS Registry Number 69657-51-8
SMILES C1=NC2=C(N1COCCO)N=C(N=C2[O-])N.[Na+]
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Aggression19.05.01.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Angioedema10.01.05.009; 23.04.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Blood creatinine increased13.13.01.004--
Blood urea13.13.01.019--Not Available
Blood urea increased13.13.01.006--Not Available
Coma17.02.09.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Delirium19.13.02.001--
Depressed level of consciousness17.02.04.002--
Diarrhoea07.02.01.001--
Disseminated intravascular coagulation01.01.02.002; 24.01.01.010--
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Dysaesthesia17.02.06.003--
Encephalopathy17.13.02.001--
Erythema multiforme10.01.03.015; 23.03.01.003--
Fatigue08.01.01.002--
Haematuria20.02.01.006; 24.07.01.047--
Haemolysis01.06.04.002--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hyperbilirubinaemia01.06.04.003; 09.01.01.003; 14.11.01.010--Not Available
Hypersensitivity vasculitis01.01.04.008; 10.02.02.017; 23.06.02.005; 24.05.02.012--Not Available
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