| ADR Ontology |
| ADR Term |
Retinoblastoma |
| ADR ID |
BADD_A10859 |
| ADR Hierarchy |
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| Description |
A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104) [MeSH] |
| MedDRA Code |
10038916 |
| MeSH ID |
D012175
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Intraocular retinoblastoma | Retinoblastoma | Retinoblastoma NOS | Retinoblastoma unilateral | Retinoblastomas | Neuroblastoma, Retinal | Neuroblastomas, Retinal | Retinal Neuroblastoma | Retinal Neuroblastomas | Glioma, Retinal | Gliomas, Retinal | Retinal Glioma | Retinal Gliomas | Eye Cancer, Retinoblastoma | Cancer, Retinoblastoma Eye | Cancers, Retinoblastoma Eye | Eye Cancers, Retinoblastoma | Retinoblastoma Eye Cancer | Retinoblastoma Eye Cancers | Glioblastoma, Retinal | Glioblastomas, Retinal | Retinal Glioblastoma | Retinal Glioblastomas | Sporadic Retinoblastoma | Retinoblastoma, Sporadic | Retinoblastomas, Sporadic | Sporadic Retinoblastomas | Familial Retinoblastoma | Familial Retinoblastomas | Retinoblastoma, Familial | Retinoblastomas, Familial | Hereditary Retinoblastoma | Hereditary Retinoblastomas | Retinoblastoma, Hereditary | Retinoblastomas, Hereditary |
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| Drugs Leading to the ADR |
| Drug ID | Drug Name | ADR Frequency (FAERS) | ADR Severity Grade (FAERS) | | BADD_D00364 | Carboplatin | 0.000112% | | | BADD_D01242 | Lamivudine | 0.002024% | | | BADD_D01376 | Melphalan | 0.000112% | |
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