Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pancreatic failure
ADR ID BADD_A10602
ADR Hierarchy
07      Gastrointestinal disorders
07.18      Exocrine pancreas conditions
07.18.02      Pancreatic disorders NEC
07.18.02.011      Pancreatic failure
Description A malabsorption condition resulting from greater than 10% reduction in the secretion of pancreatic digestive enzymes (LIPASE; PROTEASES; and AMYLASE) by the EXOCRINE PANCREAS into the DUODENUM. This condition is often associated with CYSTIC FIBROSIS and with chronic PANCREATITIS. [MeSH]
MedDRA Code 10079281
MeSH ID D010188
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Insufficiency pancreatic | Pancreatic insufficiency | Pancreatic exocrine insufficiency | Pancreatic failure | Exocrine Pancreatic Insufficiency | Exocrine Pancreatic Insufficiencies | Insufficiencies, Exocrine Pancreatic | Insufficiency, Exocrine Pancreatic | Pancreatic Insufficiencies, Exocrine | Pancreatic Insufficiency, Exocrine | Pancreatic Insufficiency | Insufficiencies, Pancreatic | Insufficiency, Pancreatic | Pancreatic Insufficiencies
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00156Apremilast0.000362%
BADD_D00283Boceprevir--
BADD_D00680Dimethyl fumarate0.001000%
BADD_D00765Empagliflozin0.000091%
BADD_D01009Gemcitabine0.000112%
BADD_D01220Ivacaftor-
BADD_D01401Metformin0.000011%
BADD_D01602Olmesartan0.000210%
BADD_D01653Paclitaxel0.000112%
BADD_D01831Prednisolone0.000052%
BADD_D01835Pregabalin0.000052%
BADD_D02029Sitagliptin0.000053%
BADD_D02105Tacrolimus0.000297%
BADD_D02470Nintedanib0.000112%
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