Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Immune effector cell-associated neurotoxicity syndrome
ADR ID BADD_A10106
ADR Hierarchy
17      Nervous system disorders
17.13      Encephalopathies
17.13.01      Encephalopathies toxic and metabolic
17.13.01.015      Immune effector cell-associated neurotoxicity syndrome
19      Psychiatric disorders
19.13      Deliria (incl confusion)
19.13.01      Confusion and disorientation
19.13.01.006      Immune effector cell-associated neurotoxicity syndrome
12      Injury, poisoning and procedural complications
12.03      Exposures, chemical injuries and poisoning
12.03.01      Poisoning and toxicity
12.03.01.065      Immune effector cell-associated neurotoxicity syndrome
Description Not Available
MedDRA Code 10083347
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
CAR T-cell-related encephalopathy syndrome | Immune effector cell-associated neurotoxicity syndrome | ICANS
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00230Bendamustine0.000224%
BADD_D00386Cefepime0.000049%
BADD_D00623Dexamethasone0.000291%
BADD_D00914Fludarabine0.000168%
BADD_D01265Levetiracetam0.000596%
BADD_D01392Mercaptopurine0.001041%
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