Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Follicular lymphoma
ADR ID BADD_A09924
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.28      Lymphomas non-Hodgkin's B-cell
16.28.08      Follicular lymphomas
16.28.08.002      Follicular lymphoma
01      Blood and lymphatic system disorders
01.15      Lymphomas non-Hodgkin's B-cell
01.15.08      Follicular lymphomas
01.15.08.002      Follicular lymphoma
Description Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the LYMPH NODES. The nodules resemble to some extent the GERMINAL CENTER of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-LYMPHOCYTES. | A low-grade malignant lymphoma of follicular pattern in which there is no clear preponderance of one cell type (small or large) over another. The large cells, cleaved or noncleaved, are often 2-3 times larger in diameter than normal lymphocytes. | Malignant lymphoma in which the majority of neoplastic cells within the follicles are large cleaved or noncleaved cells. The degree to which the follicular center cells retain their ability to form follicles varies with the state of B-cell transformation. | A low-grade malignant lymphoma of predominantly follicular pattern. Follicles are of relatively uniform size and shape and the cells are usually somewhat larger than normal lymphocytes. Nuclei are irregular with prominent indentations and cytoplasm can rarely be identified. Cells exhibiting these characteristics are often called centrocytes. [MeSH]
MedDRA Code 10085128
MeSH ID D008224
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Nodular (follicular) lymphoma | Follicular B-cell non-Hodgkin's lymphoma | Pediatric-type follicular lymphoma | Duodenal-type follicular lymphoma | In situ follicular lymphoma | Follicular B-cell non-Hodgkin's lymphoma, unclassifiable | In situ follicular neoplasia | Paediatric-type follicular lymphoma | Follicular lymphoma | Lymphoma, Follicular | Follicular Lymphomas | Lymphomas, Follicular | Follicular Lymphoma | Follicular Lymphoma, Giant | Follicular Lymphomas, Giant | Giant Follicular Lymphomas | Lymphomas, Giant Follicular | Lymphoma, Giant Follicular | Lymphoma, Nodular | Lymphomas, Nodular | Nodular Lymphoma | Nodular Lymphomas | Brill-Symmers Disease | Brill Symmers Disease | Disease, Brill-Symmers | Giant Follicular Lymphoma | Lymphoma, Follicular, Grade 1 | Follicular Lymphoma, Grade 1 | Lymphoma, Mixed-Cell, Follicular | Follicular Mixed-Cell Lymphoma | Follicular Mixed Cell Lymphoma | Follicular Mixed-Cell Lymphomas | Lymphoma, Follicular Mixed-Cell | Lymphomas, Follicular Mixed-Cell | Mixed-Cell Lymphomas, Follicular | Lymphoma, Follicular, Mixed Cell | Lymphoma, Follicular, Mixed Lymphocytic-Histiocytic | Mixed-Cell Lymphoma, Follicular | Mixed Cell Lymphoma, Follicular | Lymphoma, Follicular, Small and Large Cleaved Cell | Lymphoma, Nodular, Mixed Lymphocytic Histiocytic | Lymphoma, Nodular, Mixed Lymphocytic-Histiocytic | Lymphoma, Nodular, Mixed Small and Large Cell | Lymphoma, Follicular, Small and Large Cleaved-Cell | Lymphoma, Follicular, Mixed Small and Large Lymphoid | Lymphoma, Follicular, Grade 3 | Follicular Lymphoma, Grade 3 | Lymphoma, Large-Cell, Follicular | Histiocytic Lymphoma, Nodular | Histiocytic Lymphomas, Nodular | Lymphoma, Nodular Histiocytic | Lymphomas, Nodular Histiocytic | Nodular Histiocytic Lymphoma | Nodular Histiocytic Lymphomas | Large Lymphoid Lymphoma, Nodular | Large-Cell Lymphoma, Follicular | Large Cell Lymphoma, Follicular | Lymphoma, Nodular, Large Follicular Center Cell | Lymphoma, Histiocytic, Nodular | Lymphoma, Large Cell, Follicular | Lymphoma, Large Lymphoid, Nodular | Lymphoma, Nodular, Large Follicular Center-Cell | Nodular Large Follicular Center-Cell Lymphoma | Nodular Large Follicular Center Cell Lymphoma | Follicular Large-Cell Lymphoma | Follicular Large Cell Lymphoma | Follicular Large-Cell Lymphomas | Large-Cell Lymphomas, Follicular | Lymphomas, Follicular Large-Cell | Lymphoma, Follicular Large-Cell | Lymphoma, Follicular Large Cell | Lymphoma, Small Cleaved-Cell, Follicular | Small Follicular Center-Cell Lymphoma | Small Follicular Center Cell Lymphoma | Lymphocytic Lymphoma, Nodular, Poorly Differentiated | Lymphoma, Small Lymphoid, Follicular | Lymphoma, Lymphocytic, Nodular, Poorly Differentiated | Lymphoma, Lymphocytic, Nodular, Poorly-Differentiated | Lymphoma, Small Cleaved Cell, Follicular | Lymphoma, Small Follicular Center-Cell | Lymphoma, Small Follicular Center Cell | Small Cleaved-Cell Lymphoma, Follicular | Small Cleaved Cell Lymphoma, Follicular | Lymphocytic Lymphoma, Nodular, Poorly-Differentiated | Lymphoma, Follicular, Grade 2 | Follicular Lymphoma, Grade 2
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00195Azathioprine--
BADD_D00230Bendamustine0.000168%
BADD_D00511Clozapine--
BADD_D01253Lenalidomide0.002821%
BADD_D01418Methotrexate0.000171%
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