Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Diffuse idiopathic skeletal hyperostosis
ADR ID BADD_A09805
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.01      Joint disorders
15.01.09      Spondyloarthropathies
15.01.09.006      Diffuse idiopathic skeletal hyperostosis
Description A disease of elderly men characterized by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions. [MeSH]
MedDRA Code 10080059
MeSH ID D004057
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Ankylosing vertebral hyperostosis | Senile ankylosing vertebral hyperostosis | Forestier disease | Forestier and Rotes-Querol syndrome | Diffuse idiopathic skeletal hyperostosis | Hyperostosis, Diffuse Idiopathic Skeletal | Diffuse Idiopathic Skeletal Hyperostosis | Vertebral Ankylosing Hyperostosis | Ankylosing Hyperostoses, Vertebral | Ankylosing Hyperostosis, Vertebral | Hyperostoses, Vertebral Ankylosing | Hyperostosis, Vertebral Ankylosing | Vertebral Ankylosing Hyperostoses | Forestier's Disease | Disease, Forestier's | Forestiers Disease | Forestier-Rotes Disease | Disease, Forestier-Rotes | Forestier Rotes Disease | Ankylosing Vertebral Hyperostosis with Tylosis | Forestier Disease | Disease, Forestier
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin0.001250%
BADD_D01213Isotretinoin0.000643%
BADD_D01401Metformin0.000008%
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