Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Seminoma
ADR ID BADD_A07687
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.25      Reproductive neoplasms male malignant and unspecified
16.25.03      Testicular neoplasms malignant
16.25.03.002      Seminoma
21      Reproductive system and breast disorders
21.13      Testicular and epididymal disorders
21.13.02      Testicular and epididymal neoplasms
21.13.02.004      Seminoma
Description A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed) [MeSH]
MedDRA Code 10039956
MeSH ID D018239
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Seminoma | Seminomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00306Budesonide0.000140%
BADD_D00364Carboplatin0.000112%
BADD_D00680Dimethyl fumarate0.000400%
BADD_D00898Finasteride0.000045%
BADD_D02464Fingolimod0.000241%
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