Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Normal pressure hydrocephalus
ADR ID BADD_A07490
ADR Hierarchy
17      Nervous system disorders
17.07      Increased intracranial pressure and hydrocephalus
17.07.01      Hydrocephalic conditions
17.07.01.002      Normal pressure hydrocephalus
Description A form of compensated hydrocephalus characterized clinically by a slowly progressive gait disorder (see GAIT DISORDERS, NEUROLOGIC), progressive intellectual decline, and URINARY INCONTINENCE. Spinal fluid pressure tends to be in the high normal range. This condition may result from processes which interfere with the absorption of CSF including SUBARACHNOID HEMORRHAGE, chronic MENINGITIS, and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp631-3) [MeSH]
MedDRA Code 10029773
MeSH ID D006850
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Low pressure hydrocephaly | Normal pressure hydrocephalus | Normal pressure hydrocephaly | Hydrocephalus, Normal Pressure | Hydrocephalus, Normal-Pressure | Normal Pressure Hydrocephalus | NPH (Normal Pressure Hydrocephalus) | NPHs (Normal Pressure Hydrocephalus) | Hakim Syndrome | Hakim Syndromes | Syndrome, Hakim | Syndromes, Hakim | Hakim's Syndrome | Hakim's Syndromes | Hakims Syndrome | Syndrome, Hakim's | Syndromes, Hakim's
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00165Aripiprazole0.000079%
BADD_D00535Crizotinib0.000112%
BADD_D00563Dabigatran0.000245%
BADD_D00775Enzalutamide0.000334%
BADD_D01253Lenalidomide0.000362%
BADD_D01470Minocycline0.000649%
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