Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Bone cancer
ADR ID BADD_A06986
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.29      Skeletal neoplasms malignant and unspecified
16.29.02      Bone neoplasms malignant (excl sarcomas)
16.29.02.002      Bone cancer
15      Musculoskeletal and connective tissue disorders
15.09      Musculoskeletal and connective tissue neoplasms
15.09.03      Malignant musculoskeletal and connective tissue neoplasms
15.09.03.012      Bone cancer
Description Tumors or cancer located in bone tissue or specific BONES. [MeSH]
MedDRA Code 10005949
MeSH ID D001859
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bone cancer | Bone cancer NOS | Carcinoma bone | Malignant neoplasm of bone and articular cartilage | Malignant neoplasm of bone and articular cartilage, site unspecified | Malignant neoplasm of bones of skull and face | Malignant neoplasm of bones of skull and face, except mandible | Malignant neoplasm of long bones of lower limb | Malignant neoplasm of lower jaw bone | Malignant neoplasm of mandible | Malignant neoplasm of pelvic bones, sacrum, and coccyx | Malignant neoplasm of ribs, sternum, and clavicle | Malignant neoplasm of scapula and long bones of upper limb | Malignant neoplasm of short bones of lower limb | Malignant neoplasm of short bones of upper limb | Malignant neoplasm of vertebral column, excluding sacrum and coccyx | Bone neoplasm malignant | Malignant neoplasm of maxilla | Malignant neoplasm of vertebral column | Bone Neoplasms | Bone Neoplasm | Neoplasm, Bone | Neoplasms, Bone | Bone Cancer | Cancer of the Bone | Cancer of Bone
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00142Anastrozole0.000159%
BADD_D00284Bortezomib0.000224%
BADD_D00511Clozapine0.002446%
BADD_D00858Everolimus0.000719%
BADD_D00912Fluconazole--
BADD_D00981Gabapentin0.000010%
BADD_D01038Goserelin0.000501%
BADD_D01119Ibrutinib0.000168%
BADD_D01253Lenalidomide0.002049%
BADD_D01260Leuprolide acetate0.005736%
BADD_D01336Macitentan0.000181%
BADD_D01401Metformin0.000005%
BADD_D01476Mirtazapine0.000120%
BADD_D01654Palbociclib0.000660%
BADD_D01662Pamidronic acid--
BADD_D01687Pazopanib0.000168%
BADD_D01798Pomalidomide0.000603%
BADD_D01834Prednisone--
BADD_D01835Pregabalin0.000052%
BADD_D01913Ranitidine0.001001%
BADD_D02026Simvastatin0.000011%
BADD_D02100Sunitinib0.000817%
BADD_D02111Tamoxifen--
BADD_D02331Valsartan0.000132%
BADD_D02375Water--
BADD_D02392Zoledronic acid--
BADD_D02407Upadacitinib--
BADD_D02412Octreotide--
BADD_D02436Atorvastatin0.000005%
BADD_D02443Tiotropium--
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