Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Angiosarcoma
ADR ID BADD_A06897
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.16      Miscellaneous and site unspecified neoplasms malignant and unspecified
16.16.03      Cardiovascular neoplasms malignant and unspecified
16.16.03.001      Angiosarcoma
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.06      Vascular neoplasms
24.03.06.003      Angiosarcoma
Description A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed) [MeSH]
MedDRA Code 10002476
MeSH ID D006394; D006394; D006394; D006394; D018323
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Angiosarcoma | Angiosarcoma NOS | Angiosarcoma stage unspecified | Haemangiosarcoma | Haemangiosarcoma NOS | Hemangiosarcoma | Haemangioendothelioma malignant | Hemangioendothelioma malignant | Epithelioid hemangioendothelioma | Epithelioid haemangioendothelioma | Hemangiosarcomas | Angiosarcomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00723Doxorubicin0.000112%
BADD_D01110Hydroxyurea0.000112%
BADD_D01253Lenalidomide0.000241%
BADD_D01418Methotrexate0.000114%
BADD_D01687Pazopanib0.000560%
BADD_D01913Ranitidine0.000038%
BADD_D02053Sofosbuvir0.000282%
BADD_D02105Tacrolimus0.000594%
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