Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Multiple organ dysfunction syndrome
ADR ID BADD_A06819
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.057      Multiple organ dysfunction syndrome
Description A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. [MeSH]
MedDRA Code 10077361
MeSH ID D009102
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
MOF | Multi organ failure | Multi-organ failure | Multiorgan failure | Multiple organ failure | Multiple organ dysfunction syndrome | Multiple Organ Failure | Multiple Organ Dysfunction Syndrome | Organ Failure, Multiple | Failure, Multiple Organ | Multiple Organ Failures | MODS | Organ Dysfunction Syndrome, Multiple
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02268Treprostinil0.000658%
BADD_D02270Tretinoin--
BADD_D02329Valproic acid0.000849%
BADD_D02344Vemurafenib0.000560%
BADD_D02345Venetoclax0.001231%
BADD_D02346Venlafaxine0.000129%
BADD_D02355Vigabatrin--
BADD_D02360Vincristine--
BADD_D02361Vincristine sulfate--
BADD_D02369Voriconazole0.078415%
BADD_D02373Warfarin0.000463%
BADD_D02375Water--
BADD_D02380Zanamivir0.000423%
BADD_D02392Zoledronic acid0.017178%
BADD_D02396Zonisamide0.000829%
BADD_D02411Voxelotor-
BADD_D02412Octreotide0.000279%
BADD_D02421Foscarnet0.000706%
BADD_D02423Fondaparinux0.004934%
BADD_D02432Glycopyrronium0.001891%
BADD_D02471Oxygen0.003717%
BADD_D02483Ribociclib0.000280%
BADD_D02487Baricitinib0.000362%
BADD_D02493Selinexor0.000168%
BADD_D02502Letermovir0.000282%
BADD_D02504Lorlatinib0.000224%
BADD_D02505Gilteritinib0.000280%
BADD_D02509Brigatinib0.000168%
BADD_D02517Enasidenib0.000112%
BADD_D02520Baloxavir marboxil0.000565%
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