Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Intraductal proliferative breast lesion
ADR ID BADD_A06707
ADR Hierarchy
21      Reproductive system and breast disorders
21.05      Breast disorders
21.05.01      Benign and malignant breast neoplasms
21.05.01.014      Intraductal proliferative breast lesion
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.10      Breast neoplasms malignant and unspecified (incl nipple)
16.10.01      Breast and nipple neoplasms malignant
16.10.01.006      Intraductal proliferative breast lesion
Description A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma. [MeSH]
MedDRA Code 10073094
MeSH ID D002285
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Carcinoma in situ of breast ductal | Ductal breast carcinoma stage I | Ductal carcinoma in situ | Intraductal breast cancer (in situ) | Noninvasive ductal carcinoma | Mammary ductal intraepithelial neoplasia | Intraductal proliferative breast lesion | Mixed ductal lobular breast carcinoma in situ | Carcinoma, Intraductal, Noninfiltrating | Carcinoma, Intraductal | Carcinomas, Intraductal | Intraductal Carcinoma | Intraductal Carcinomas | DCIS | Ductal Carcinoma In Situ | Intraductal Carcinoma, Noninfiltrating | Carcinoma, Noninfiltrating Intraductal | Carcinomas, Noninfiltrating Intraductal | Intraductal Carcinomas, Noninfiltrating | Noninfiltrating Intraductal Carcinoma | Noninfiltrating Intraductal Carcinomas | Atypical Ductal Hyperplasia | Atypical Ductal Hyperplasias | Ductal Hyperplasia, Atypical | Ductal Hyperplasias, Atypical | Hyperplasia, Atypical Ductal | Hyperplasias, Atypical Ductal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000132%
BADD_D00142Anastrozole0.000318%
BADD_D00680Dimethyl fumarate0.001000%
BADD_D00898Finasteride0.000045%
BADD_D01136Imatinib0.000168%
BADD_D01253Lenalidomide0.001929%
BADD_D01258Leucovorin0.002726%
BADD_D01281Levonorgestrel0.003546%
BADD_D01298Liraglutide--
BADD_D01798Pomalidomide0.000241%
BADD_D01834Prednisone0.000009%
BADD_D01913Ranitidine0.000075%
BADD_D02165Teriflunomide0.000362%
BADD_D02170Testosterone0.000091%
BADD_D02464Fingolimod0.002411%
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