Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Postural orthostatic tachycardia syndrome
ADR ID BADD_A06159
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.02      Rate and rhythm disorders NEC
02.03.02.020      Postural orthostatic tachycardia syndrome
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.01      Autonomic nervous system disorders
17.05.01.019      Postural orthostatic tachycardia syndrome
Description A syndrome of ORTHOSTATIC INTOLERANCE combined with excessive upright TACHYCARDIA, and usually without associated ORTHOSTATIC HYPOTENSION. All variants have in common an excessively reduced venous return to the heart (central HYPOVOLEMIA) while upright. [MeSH]
MedDRA Code 10063080
MeSH ID D054972
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Postural orthostatic tachycardia syndrome | Orthostatic tachycardia | Postural Orthostatic Tachycardia Syndrome | Postural Tachycardia Syndrome | Syndrome, Postural Tachycardia | Tachycardia Syndrome, Postural
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01280Levomilnacipran hydrochloride--
BADD_D01656Paliperidone--
BADD_D01657Paliperidone palmitate--
BADD_D01951Risperidone--
BADD_D02010Sertraline0.000013%
BADD_D02047Sodium oxybate0.000590%
BADD_D02236Tofacitinib0.000362%
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