Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Non-small cell lung cancer
ADR ID BADD_A06004
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.08      Respiratory tract neoplasms
22.08.01      Lower respiratory tract neoplasms
22.08.01.002      Non-small cell lung cancer
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.19      Respiratory and mediastinal neoplasms malignant and unspecified
16.19.01      Non-small cell neoplasms malignant of the respiratory tract cell type specified
16.19.01.001      Non-small cell lung cancer
Description A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. [MeSH]
MedDRA Code 10061873
MeSH ID D002289
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Non-small cell lung cancer NOS | Non-small cell lung cancer | Progression of non-small cell lung cancer | Non-squamous non-small cell lung cancer | Carcinoma, Non-Small-Cell Lung | Carcinoma, Non Small Cell Lung | Carcinomas, Non-Small-Cell Lung | Lung Carcinoma, Non-Small-Cell | Lung Carcinomas, Non-Small-Cell | Non-Small-Cell Lung Carcinomas | Nonsmall Cell Lung Cancer | Non-Small-Cell Lung Carcinoma | Non Small Cell Lung Carcinoma | Carcinoma, Non-Small Cell Lung | Non-Small Cell Lung Cancer
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00047Afatinib0.001735%
BADD_D00157Aprepitant--
BADD_D00414Ceritinib0.002630%
BADD_D00511Clozapine--
BADD_D00535Crizotinib0.010185%
BADD_D00566Dabrafenib0.000112%
BADD_D00623Dexamethasone0.000218%
BADD_D00800Erlotinib0.000918%
BADD_D00914Fludarabine0.000112%
BADD_D01629Osimertinib0.000336%
BADD_D01653Paclitaxel0.001119%
BADD_D02058Sorafenib0.000112%
BADD_D02105Tacrolimus0.000446%
BADD_D02192Thalidomide0.000362%
BADD_D02363Vinorelbine0.000112%
BADD_D02470Nintedanib0.000280%
BADD_D02480Alectinib0.000280%
BADD_D02509Brigatinib0.006044%
BADD_D02540Capmatinib0.001847%
BADD_D02553Entrectinib0.000224%
BADD_D02573Mobocertinib0.001231%
BADD_D02596Sotorasib0.006660%
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