Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Aortic rupture
ADR ID BADD_A05730
ADR Hierarchy
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.04      Site specific vascular disorders NEC
24.03.04.009      Aortic rupture
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.11      Cardiovascular injuries
12.01.11.007      Aortic rupture
Description The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA. [MeSH]
MedDRA Code 10060874
MeSH ID D001019
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Aortic rupture | Ascending aortic rupture | Descending thoracic aorta rupture | Abdominal aortic rupture | Aortic Rupture | Aortic Ruptures | Rupture, Aortic | Ruptures, Aortic | Aortic Aneurysm, Ruptured | Aneurysm, Ruptured Aortic | Aneurysms, Ruptured Aortic | Aortic Aneurysms, Ruptured | Ruptured Aortic Aneurysms | Ruptured Aortic Aneurysm
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000043%
BADD_D00195Azathioprine0.000313%
BADD_D00504Clopidogrel0.000021%
BADD_D00563Dabigatran0.000489%
BADD_D01275Levofloxacin0.000211%
BADD_D01442Metoclopramide0.000490%
BADD_D01633Oxaliplatin--
BADD_D01954Rivaroxaban0.000158%
BADD_D02105Tacrolimus0.000594%
BADD_D02236Tofacitinib0.000241%
BADD_D02373Warfarin0.000028%
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