Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Blue toe syndrome
ADR ID BADD_A05647
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.01      Cardiac and vascular procedural complications
12.02.01.005      Blue toe syndrome
24      Vascular disorders
24.01      Embolism and thrombosis
24.01.02      Peripheral embolism and thrombosis
24.01.02.004      Blue toe syndrome
Description A condition that is caused by recurring atheroembolism in the lower extremities. It is characterized by cyanotic discoloration of the toes, usually the first, fourth, and fifth toes. Discoloration may extend to the lateral aspect of the foot. Despite the gangrene-like appearance, blue toes may respond to conservative therapy without amputation. [MeSH]
MedDRA Code 10059126
MeSH ID D018438
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Purple toes syndrome | Blue toe syndrome | Blue Toe Syndrome | Syndrome, Blue Toe
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000054-oxo-3-(3-oxo-1-phenylbutyl)chromen-2-olate--
BADD_D00151Apixaban0.000139%
BADD_D00765Empagliflozin0.000200%
BADD_D01954Rivaroxaban0.000127%
BADD_D02373Warfarin0.000196%
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