Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cerebral vasoconstriction
ADR ID BADD_A05646
ADR Hierarchy
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.02      Central nervous system vascular disorders NEC
17.08.02.012      Cerebral vasoconstriction
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.025      Cerebral vasoconstriction
Description Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN). [MeSH]
MedDRA Code 10059109
MeSH ID D020301
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cerebral arterial spasm | Cerebral arteriospasm | Spasm cerebrovascular | Vasospasm cerebral | Cerebrovascular spasm | Cerebral vasoconstriction | Multifocal vasoconstriction of cerebral arteries | Vasospasm, Intracranial | Intracranial Vasospasms | Vasospasms, Intracranial | Intracranial Vasospasm | Angiospasm, Intracranial | Intracranial Vascular Spasm | Intracranial Vascular Spasms | Spasm, Intracranial Vascular | Spasms, Intracranial Vascular | Vascular Spasm, Intracranial | Vascular Spasms, Intracranial | Intracranial Angiospasm | Angiospasms, Intracranial | Intracranial Angiospasms | Cerebral Vasospasm | Cerebral Vasospasms | Vasospasm, Cerebral | Vasospasms, Cerebral | Cerebrovascular Spasm | Cerebrovascular Spasms | Spasm, Cerebrovascular | Spasms, Cerebrovascular | Cerebral Angiospasm | Angiospasm, Cerebral | Angiospasms, Cerebral | Cerebral Angiospasms | Cerebral Artery Spasm | Artery Spasm, Cerebral | Artery Spasms, Cerebral | Cerebral Artery Spasms | Spasm, Cerebral Artery | Spasms, Cerebral Artery
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00371Carmustine0.000112%
BADD_D00417Cetirizine0.000029%
BADD_D00551Cyclosporine0.000166%
BADD_D00560Cytarabine0.000392%
BADD_D00809Escitalopram0.000028%
BADD_D00932Fluoxetine0.000148%
BADD_D00981Gabapentin0.000016%
BADD_D01111Hydroxyzine0.000037%
BADD_D01442Metoclopramide0.000294%
BADD_D01831Prednisolone0.000052%
BADD_D01876Pseudoephedrine0.000326%
BADD_D01909Ramipril0.000233%
BADD_D01933Ribavirin0.003956%
BADD_D01954Rivaroxaban0.000095%
BADD_D02010Sertraline0.000013%
BADD_D02011Sertraline hydrochloride--
BADD_D02028Sirolimus0.000134%
BADD_D02098Sumatriptan0.000139%
BADD_D02105Tacrolimus0.000743%
BADD_D02373Warfarin0.000028%
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