Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Varices oesophageal
ADR ID BADD_A05394
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.06      Hepatic vascular disorders
09.01.06.009      Varices oesophageal
07      Gastrointestinal disorders
07.15      Gastrointestinal vascular conditions
07.15.05      Oesophageal varices
07.15.05.001      Varices oesophageal
24      Vascular disorders
24.10      Venous varices
24.10.02      Gastrointestinal varicosities and haemorrhoids
24.10.02.004      Varices oesophageal
Description Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL). [MeSH]
MedDRA Code 10056091
MeSH ID D004932
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Esophageal varices | Esophageal varices in diseases classified elsewhere | Esophageal varices in diseases classified elsewhere, without mention of bleeding | Esophageal varices without mention of bleeding | Oesophageal varices in cirrhosis of liver | Oesophageal varices NOS | Oesophageal varices without mention of bleeding | Varices esophageal | Esophageal varices in cirrhosis of liver | Varices oesophageal | Gastrooesophageal varices | Gastroesophageal varices | Esophageal and Gastric Varices | Gastric Varix | Varices, Gastric | Varix, Gastric | Gastric Varices | Esophageal Varices | Esophageal Varix | Varices, Esophageal | Varix, Esophageal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01687Pazopanib0.000112%
BADD_D01783Pirfenidone0.000241%
BADD_D01867Propranolol0.000107%
BADD_D01933Ribavirin0.055382%
BADD_D01938Rifaximin0.000804%
BADD_D01954Rivaroxaban0.000285%
BADD_D01978Ruxolitinib0.000508%
BADD_D02018Sildenafil0.000107%
BADD_D02029Sitagliptin0.000080%
BADD_D02053Sofosbuvir0.001411%
BADD_D02058Sorafenib0.000448%
BADD_D02100Sunitinib0.000112%
BADD_D02154Tenofovir0.005816%
BADD_D02199Thioguanine--
BADD_D02373Warfarin0.000182%
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