Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Xanthoma
ADR ID BADD_A04668
ADR Hierarchy
14      Metabolism and nutrition disorders
14.08      Lipid metabolism disorders
14.08.04      Lipid metabolism and deposit disorders NEC
14.08.04.010      Xanthoma
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.03      Dermal and epidermal conditions NEC
23.03.03.047      Xanthoma
Description A condition marked by the development of widespread xanthomas, yellow tumor-like structures filled with lipid deposits. Xanthomas can be found in a variety of tissues including the SKIN; TENDONS; joints of KNEES and ELBOWS. Xanthomatosis is associated with disturbance of LIPID METABOLISM and formation of FOAM CELLS. [MeSH]
MedDRA Code 10048214
MeSH ID D014973
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Eruptive xanthoma | Planar xanthoma | Plane xanthoma | Tendinous xanthoma | Tendon xanthoma | Tuberous xanthoma | Tuberous xanthomata | Xanthoma | Xanthomatosis | Xanthomatoses | Xanthomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00452Cholestyramine resin--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01120Ibuprofen0.000009%
BADD_D01213Isotretinoin--
BADD_D01311Lomitapide0.000109%
BADD_D01563Nicotinate--
BADD_D01567Nilotinib0.000112%
BADD_D01599Olanzapine0.000631%
BADD_D01687Pazopanib0.000381%
BADD_D02329Valproic acid0.000150%
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