Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Vitamin B12 deficiency
ADR ID BADD_A04604
ADR Hierarchy
14      Metabolism and nutrition disorders
14.12      Vitamin related disorders
14.12.02      Water soluble vitamin deficiencies
14.12.02.004      Vitamin B12 deficiency
Description A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848) [MeSH]
MedDRA Code 10047609
MeSH ID D014806
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Dietary B12 deficiency | Vitamin B12 absorption decreased | Vitamin B12 deficiency | Cobalamin deficiency | Hypocobalaminemia | Hypocobalaminaemia | Vitamin B 12 Deficiency | Vitamin B12 Deficiency | Deficiency, Vitamin B12 | Deficiencies, Vitamin B12 | Vitamin B12 Deficiencies | Deficiency, Vitamin B 12
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01898Rabeprazole--
BADD_D01966Ropinirole--
BADD_D02029Sitagliptin0.000053%
BADD_D02047Sodium oxybate0.000590%
BADD_D02059Sorbitol--
BADD_D02100Sunitinib0.000112%
BADD_D02107Tafamidis0.001346%
BADD_D02165Teriflunomide0.000241%
BADD_D02247Topiramate0.000050%
BADD_D02392Zoledronic acid0.004294%
BADD_D02439Levodopa0.000367%
BADD_D02464Fingolimod0.002146%
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ADReCS-Target
ADR Term Drug Name Target