Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Sorbitol
Drug ID BADD_D02059
Description A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Indications and Usage Used as a non-stimulant laxative via an oral suspension or enema.
Marketing Status approved
ATC Code A06AD18; A06AG07; B05CX02; V04CC01
DrugBank ID DB01638
KEGG ID D00096
MeSH ID D013012
PubChem ID 5780
TTD Drug ID D09MXS
NDC Product Code 50516-005; 51552-0096; 51552-0216; 0338-0295; 57896-758
UNII 506T60A25R
Synonyms Sorbitol | Glucitol | Yal | Sorbilax | klysma Sorbit | Medevac
Chemical Information
Molecular Formula C6H14O6
CAS Registry Number 50-70-4
SMILES C(C(C(C(C(CO)O)O)O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acidosis14.01.03.002--
Angina pectoris02.02.02.002; 24.04.04.002--
Back pain15.03.04.005--
Blood glucose increased13.02.02.002---
Chills08.01.09.001; 15.05.03.016--
Dehydration14.05.05.001--
Diarrhoea07.02.01.001--
Dry mouth07.06.01.002--
Electrolyte imbalance14.05.01.002---
Hyperosmolar state14.05.01.005---
Hypersensitivity10.01.03.003--
Hypervolaemia02.05.04.019; 14.05.06.003---
Hypotension24.06.03.002--
Lung disorder22.02.07.001---
Nausea07.01.07.001--
Oedema08.01.07.006; 14.05.06.010---
Pain08.01.08.004--
Polyuria20.02.03.002---
Pulmonary congestion02.05.02.002; 22.01.03.002; 24.03.08.001---
Rhinitis11.01.13.004; 22.07.03.006--
Seizure17.12.03.001--
Tachycardia02.03.02.007---
Thirst08.01.09.021; 14.03.02.007---
Urinary retention20.02.02.011--
Urticaria10.01.06.001; 23.04.02.001--
Vertigo04.04.01.003; 17.02.12.002--
Vision blurred06.02.06.007; 17.17.01.010--
Vitamin B12 deficiency14.12.02.004---
Vomiting07.01.07.003--
Respiratory tract congestion22.02.07.003---
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ADReCS-Target
Drug Name ADR Term Target
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