Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Tooth hypoplasia
ADR ID BADD_A04343
ADR Hierarchy
07      Gastrointestinal disorders
07.09      Dental and gingival conditions
07.09.08      Dental developmental disorders and anomalies
07.09.08.003      Tooth hypoplasia
03      Congenital, familial and genetic disorders
03.04      Gastrointestinal tract disorders congenital
03.04.01      Dental disorders congenital
03.04.01.002      Tooth hypoplasia
Description An acquired or hereditary condition due to deficiency in the formation of tooth enamel (AMELOGENESIS). It is usually characterized by defective, thin, or malformed DENTAL ENAMEL. Risk factors for enamel hypoplasia include gene mutations, nutritional deficiencies, diseases, and environmental factors. | A type of developmental disturbance of AMELOGENESIS involving permanent INCISORS and first permanent MOLARS. It is characterized by asymmetrical enamel defects with severe hypomineralization. [MeSH]
MedDRA Code 10044041
MeSH ID D003744; D003811; D000567
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Dental development impaired | Development dental impaired | Dysplasia tooth | Enamel hypoplasia | Hypoplasia enamel | Hypoplasia tooth | Odontogenesis impaired | Tooth formation retarded | Tooth hypoplasia | Dentinogenesis imperfecta | Capdepont's disease | Stainton's syndrome | Amelogenesis imperfecta | Dental Enamel Hypoplasia | Hypoplastic Enamel | Enamel, Hypoplastic | Enamel Hypoplasia, Dental | Hypoplasia, Dental Enamel | Enamel Agenesis | Ageneses, Enamel | Agenesis, Enamel | Enamel Ageneses | Enamel Hypoplasia | Enamel Hypoplasias | Hypoplasia, Enamel | Hypoplasias, Enamel | Molar Incisor Hypomineralization | Hypomineralization, Molar Incisor
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00718Doxazosin--
BADD_D00725Doxycycline--
BADD_D01333Lymecycline--
BADD_D01470Minocycline--
BADD_D01471Minocycline anion--
BADD_D02180Tetracycline anion--
BADD_D02181Tetracycline hydrochloride--
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